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Ryze - The handball master
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So, damage of your Overload = [40/65/90/115/140 depending on spell level] + [8% of your maximum mana] + [20% of your ability power]
Imagine you are 18 level, you have 5000 mana and 250 ability power, then your damage of Overload would be  +  +  = 590 damage! You may say, That's almost impossible... but it isn't!
So, lets start with Sapphire Crystal, Mana Potion and Health Potion. At first level you should have something about 700 mana which causes perfect damage for the start against classic magic resist and low HP champions (30-36 magic resist). Your task is to hit as many times as it is possible. You have to harras all the game, be fast, use hit and run and kite enemy all the time. That's the key. But remember, in early game you're weak! So take care of ganks (the best solution is to buy some ward).
Core build is:
Tear of Goddess + Boots + Catalyst of Protector