Malz has very big harassment in lane since his creature(passive) is attracted to his E, if the curse gets onto an enemy champion it will do a significant amount. And plus you can farm all
day with that E of his because it moves onto a target after it kills a target AND refunds a nice amount of mana if you kill a target with it.
Malz can destroy with his E,Q,W,R,E combo. Now Malz's Q may take some practice to aim but after awhile you will be aiming like a pro. The W will add an extra DPS to the mix if you can R the enemy on top of your W.
Malz's R is a supress so never target Olaf with it. WHY DO YOU ASK WHY NOT OLAF?? Well Olaf's
R disables supress's and stuns and all that good ****. Just to let you know Malz's R can be silenced or stunned or knocked-up or whatever while he is in the middle of his supress.
Don't forget Archangels Staff will eventually become Seraph's Embrace so you can use that passive shield and it just might save your life.

Pros

Malz can wreck - hard

Malz can harm many enemies if abilities are aimed right

Malz loves many low hp champs in one place, just E on one and walk(or float) away

Cons

Malz can feed - hard

Malz pushes lanes very hard so enemy ganks may be often

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IGNITE

Ignite is a pretty useful tool to pickup early kills with Malz. It provides an extra DPS which
used more for aggresive players, like me, but I do think you have to be a bit more aggressive
with Malz than other champions.

GHOST

I love ghost because it acts as a gap closer and opener, but even better you can still catch
up to opponents that flash away from you(unless it's over the wall).

OTHER POSSIBILITIES

EXHAUST

Exhaust is a nice tool if you are versing a more attack oriented champion, like teemo. If being
used switch if out for ghost.

FLASH

Flash is a pretty decent gap closer but opponents can still catch up to you, don't think
you are safe after you flash. Switch out for ghost if being used.

HEAL

Heal is good when versing early game damage champions. I don't highly recommend it though.
You can switch it out for whatever, it can help you earn a kill or escape death.

Don't use the other spells with Malz.

Im not going to be like these masteries do that and those runes do that, because the rune tells
you and if you are going to be a dedicated Malz player to this guide then trust me those are
my runes and masteries and they have been working for years. YEARS??!?!?! Yes I have been playin
Malz quite awhile and he is my favorite mid champion to play because he PWNS or whatever you people say nowadays. ANYWAYS you have to know a few things about Malz before you start playing him. Don't be frustrated when a peice of **** can play better than you the first few games.
With Malz you must be careful about pushing the lane. If you push too far too often you will be ganked and die. You need to control your E on minion waves. Put E on every other wave or something like that so your lane won't be under the enemy tower. Whenever you start getting a bit too low on mana start to use your abilities more sparingly and use E whenever there's a good 5-7 minions to kill so you can gain some mana back. E won't be able to kill minions by itself till later in the game so make sure you keep auto-attacking those minions!!!
Remember earlier I was talking about being ganked? Well is you have got this feeling that you can take the jungler and mid and come out alive with a double kill then do it. You are going to want to try to get both of them silenced from your Q. Then put W down and make sure it's dealing damage to both of them. Then put E on the enemy with lower HP. Next R the one with the higher HP. Then keep focusing the one with the lower HP. Remember you have got to have that special feeling or this whole thing I just explained wouldn't do any good.

This should be about when laning is coming to a close and teamfights are starting to break out. What you have to do as Malz in those teamfights is to pick off the little piggy who strayed too far from home(if you know what I mean?). I mean that there will be an initiaor on the enemy team and when he/she dives in you DESTROY him/her along with your team (but don't use your R if it's the tank or somebody like Cho'Gath or Amumu). So now the fight will start out as a 5v4. BOOMa guaranteed victory!!!!!!