This is a pretty basic Vayne guide using my experience playing many many games on this champion, using my own thoughts and input into items, gameplay and more. My goal is to inform and help anyone who may need it to get better at playing Vayne. Thanks for reading!

The meta for AD Carrys is to run Flash and Heal. These are two very good spells for surviving in lane and team fights. It is very important Vayne has as many tools as possible to stay alive.

Maxing Silver Bolts (W) is the most efficient item to max, especially when building attack speed. IF you decide to go damage first, you can max tumble (Q) but your DPS wont be as high. Put points in Final Hour (R) whenever you can. The damage scaling is very good.

Lets discuss the reason for the items I have chosen for this build. First, I believe Doran's Blade is a better choice than Cull. The HP and lifesteal is better in lane vs lane bullies that Vayne struggles against

. Second, I take Rapid Fire Cannon over Stattik Shiv and Phantom dancer because of the energized auto with extra range. That extra range helps Vayne trade autos in lane by utilizing her passive to harass enemies running away, back turned, cs'ing, etc.

Next You can either go Blade of the Ruined King or Phantom Dancer. I suggest PD if you are ahead and can afford to fight without lifesteal. Even though its not building AD I think of it as the damage route, putting out as many attacks and crits as possible. For most situations because Vayne struggles in a lot of lanes, you can build BOTRK for lifesteal and strength in 1v1s using the active ability and lifesteal to stay alive and potentially outplay. Using the active on BOTRK while in ultimate is one of the best things a Vayne can do to kite and take down tanks, stay alive, or 1v1 burst.

Next, because you only build a +25 AD item or another AS item, to spike your damage output go for Infinity Edge. The passive makes your AS item buys more worth it.

After those core items, look defensive. Quick Silver Sash is vital for decisive teamfights. Banshees Veil is vs someone like thresh blitz or rengar. The lifesteal from Mercurial Scimitar is also good.

Lastly, if the enemy team is stacking armor, Lord Dominiks Regards is a great item for deep into late game. The % max health shred is big.

I earned Gold basically by playing Vayne, and ADC in general. But she has a lot of tough matchups in lane and good players can punish Vaynes weak early game and slip ups. If your support is someone like Janna or Soraka, those matchups should not matter as much and give you a better chance at winning in Ranked.

While farming in lane, use Tumble to reposition after killing a minion or to get in position to kill one. Also use it to reset your auto attacks and push faster. Pay attention to your critical strikes and how damage much your 3rd hit on Silver Bolts will do. During mid and late game Vayne can take Dragons and Barons easily with just 1 or two other teammates in a lot of situations.

Two points I Want to touch on are using Condemn (E) and Final Hour (R). These are two unique abilities with a lot of usage. First, always pay attention to the angle that enemies are standing parallel to a wall. Using tumble or flash to knock someone into a wall for a stun with Condemn is a great engage, disengage, fighting, and surviving tool. Using Vayne Ultimate allows you to go invisible for a few seconds after tumbling. Use this stealth to as much of an advantage as possible. You reappear when attacking, so use the stealth to get a position around or on another side of your enemy to set up stuns and make it harder for them to target you. A good way to use Vayne ultimate is aggressively. Especially during 1v1s and skirmishes, if you use your ultimate right away and just start smacking people with autos and immediately going invisible, it can cause a lot of chaos and set kills up for your team. You also get enhanced movement speed through your passive while Final Hour is active. Use it to chase down enemies and clean up fights. Another use is when a tank or assassin jumps on you, use Final hour right away to go stealth mode and buy time for your team to arrive. Coupled with Quick Silver Sash it works very well.

PROS: High damage, High dps, Tank shredder, works well in all team comps with tanks, very strong late game, some mobility, VERY fun champion
CONS: Very squishy, vulnerable to hard cc and ganks, high-ish skill cap (it's more than just auto attacking), doesn't work well with every support, weak early game, can be a frustrating champion to play before you get used to her and can stay alive well

***STAY ALIVE***

Use Final Hour to disengage during fights so your team can use abilities while you stay protected and hit whoever is closest to you with auto attacks.

If you're ahead you can take on an assassin type role and pick off squishies with your stealth and disengage by standing on the side outside of a fight and striking when best.

Try to stay with your support for protection, ask team to watch for when they need to peel for you. You are the DPS of the team when playing vayne, do all you can and cooperate with your team in order to stay alive and get off as many attacks as possible.

You can kite and harass front line tanks with tumble and RapidFire Cannon. The risk should not be high enough in a 5v5 teamfight unless there is a blitzcrank etc.

Stay behind your tanks and keep alert for flanking assasins.

If your team is heavily winning a fight before you get there, use Final Hour to clean up the remaining kills.