This guide has not yet been updated for the current season. Please keep this in mind while reading. You can see the most recently updated guides on the browse guides page
Thank You!
Your votes and comments encourage our guide authors to continue
creating helpful guides for the League of Legends community.
Runes: Vayne PTA - Safe (New Players)

+10% Attack Speed
+9 Adaptive (5.4 AD or 9 AP)
+6 Armor
Spells:

Flash
Heal
Items
Ability Order
Night Hunter (PASSIVE)
Vayne Passive Ability
Threats & Synergies
Threats
Synergies
Show All
Extreme Threats

Caitlyn
Her range is superior to your by far. If the support has a root you can be into a perma root situation with her W. Only way to contest her is with a gank or a hard CC champion like Pantheon or Nautilus.

Yuumi
Yuumi is very strong with Vayne as she can heal Vayne giving her high amounts of movement speed and can Ult to stop the enemy ADC from kiting.
Synergies

Yuumi
Yuumi is very strong with Vayne as she can heal Vayne giving her high amounts of movement speed and can Ult to stop the enemy ADC from kiting.






















You must be logged in to comment. Please login or register.