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Vayne Build Guide by cyb3r1a

ADC Vayne ADC Season 15 Cheat Sheet

ADC Vayne ADC Season 15 Cheat Sheet

Updated on June 14, 2025
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League of Legends Build Guide Author cyb3r1a Build Guide By cyb3r1a 1,396 Views 0 Comments
1,396 Views 0 Comments League of Legends Build Guide Author cyb3r1a Vayne Build Guide By cyb3r1a Updated on June 14, 2025
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Choose Champion Build:

  • LoL Champion: Vayne
    On-Hit + Threats
  • LoL Champion: Vayne
    Crit Vayne
  • LoL Champion: Vayne
    Trinity Force

Recommended Items

Blade of the Ruined King Guinsoo's Rageblade Berserker's Greaves Terminus Jak'Sho, The Protean Guardian Angel

Runes: Lethal Tempo

1 2
Precision
Lethal Tempo
Triumph
Legend: Alacrity
Coup de Grace

Resolve
Second Wind
Overgrowth
Bonus:

+10% Attack Speed
+10-180 Bonus Health
+10-180 Bonus Health

Spells:

1 2 3 4
LoL Summoner Spell: Barrier

Barrier

LoL Summoner Spell: Flash

Flash

Items

Starting Items
Doran's Blade Health Potion Stealth Ward
Boots
Berserker's Greaves Plated Steelcaps Boots of Swiftness
On-Hit (Hard/Unplayable Matchups)
Core Items (Hard/Unplayable Matchups)
Vampiric Scepter Blade of the Ruined King Guinsoo's Rageblade
Ideal 3rd + 4th
Terminus Jak'Sho, The Protean
3rd + 4th + 5th into AP bot lane or AP heavy teams
Wit's End Terminus Jak'Sho, The Protean
Situational
Kraken Slayer Randuin's Omen Spirit Visage Guardian Angel Kaenic Rookern
On-Hit (Snowball/Easy Matchups)
Core Items (Snowball/Easy Matchups)
Kraken Slayer Guinsoo's Rageblade Slightly Magical Boots
Ideal 3rd + 4th
Terminus Jak'Sho, The Protean
3rd + 4th + 5th into AP bot lane or AP heavy teams
Wit's End Terminus Jak'Sho, The Protean
Situational
Blade of the Ruined King Randuin's Omen Spirit Visage Guardian Angel Kaenic Rookern
Example Build
Blade of the Ruined King Guinsoo's Rageblade Berserker's Greaves Terminus Jak'Sho, The Protean Guardian Angel

Ability Order

Night Hunter (PASSIVE)

Vayne Passive Ability

Tumble (Q)
Q

Silver Bolts (W)
W

Condemn (E)
E

Final Hour (R)
R

Threats & Synergies

Threats Synergies
Extreme Major Even Minor Tiny
Show All
None Low Ok Strong Ideal
Extreme Threats
Ideal Synergies
Synergies
Ideal Strong Ok Low None
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Vayne counters well

Ziggs
3.8 CR
Ezreal
4 CR
Kalista
4.2 CR

Vayne gets countered

Nilah
5.8 CR
Aphelios
5.6 CR
Smolder
5.4 CR
More Vayne Counters
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Vayne counters well

Ziggs
3.8 CR
Ezreal
4 CR
Kalista
4.2 CR

Vayne gets countered

Nilah
5.8 CR
Aphelios
5.6 CR
Smolder
5.4 CR
More Vayne Counters
League of Legends Build Guide Author cyb3r1a
cyb3r1a Vayne Guide
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