LoL Best Vayne Build Guides 2025
Build guides for Vayne on MOBAFire. Find recommended items and runes by high ranked players to learn the best Vayne builds. Create your own champion guide!
2025, Season 2 Guides // Patch 25.11
[25.11] VAYNE "ALL SHALL TREMBLE" SEASON 15 BUILD (2025)
2025, Season 2 Guides // Patch 25.10
An Orbwalker's Guide to Vayne
Here's a step-by-step guide for Vayne top lane in Patch 25.10, optimized for climbing ranked and destroying tanks.
2025, Season 2 Guides // Other Patches
Challenger BR - Top 1 Vayne World S15 Guide !
[15.09] Vayne guide by misterfirstblood v2
2025, Season 2 Builds // Patch 25.11
vayne
2025, Season 2 Builds // Patch 25.10
VAYNE LETHALITY
Vayne - Jack of all Trades (JOTA)
2025, Season 2 Builds // Other Patches
ULTIMATE TURBO CHINESE BUILD
2025, Season 1 Guides
only vayne guide you will ever need
2025, Season 1 Builds