I go 1/14/15, this gives me the best mix of survivability and jungle control. With these masteries you can basically clear the jungle from 1-6 using the superior route with just a vampiric sceptre and never really go below full health (if you really wanted to).
16/0/14 makes you fast-ish and gives you a bit more jungle control - at the disadvantage of survivability.
21/0/9 is also viable-ish, it's the fastest, but gives you less jungle control and survivability in general.
16/0/14 makes you fast-ish and gives you a bit more jungle control - at the disadvantage of survivability.
21/0/9 is also viable-ish, it's the fastest, but gives you less jungle control and survivability in general.

I'll put 21/0/9 as a viable alternative in my guide (yes, if you haven't guessed, I'm writing a guide), but right now I'm just trying to figure out which setup to have in my core build. 1/14/15 has worked well for me in the past (ridiculous sustain), but I'm wondering if 16/0/14 would be more efficient.

Thanks to Hoppermh for the sig!
^If you have that many points outside utility you might as well go offense, because that will help more than a little more defense.
"Blizzard spoke thus; Thou shalt not BM. And the players replied Nay, I shall Play my hand with Lethal already on the board. And so Blizzard sent unto them this Brawl of Yogg, As a lesson for their sins of Pride and Greed, for he is the Prophet of Madness and RNG. On that day, the tavern descended into an era of chaos and darkness, until the weekend passed and everyone forgot all about it. Amen. Book of SMOrc, Verse 20, Chapter 4." - Feam T
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Right now I'm weighing 1/14/15 and 16/0/14. What do you think of these options? Are there any other setups I should be considering?