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Build: the build itself is okay, but i have to tell you that; singed has 0 burst, no matter what you do he still is a sustained damage for the team, he cannot deliver a burst, he can only damage over time, which makes it a must for him to be able to survive for a long time during a fight, thus, having only hp is not enough. with that vast amount of hp, you should get magic resist and armor, you get some armor from the guardian angel but its not much, and you barely get any magic resist, so even if you will get fed you are easily countered by Madred's Bloodrazor , and whatever tankiness you had untill now will go kapoot from that. i recommend buying after rod of ages Force of Nature that will cover up the need for survivability without harming the damage output too much.
also i recommend you try Sunfire Aegis it will give you some defense and hp, and it coops great with your poison, if i am correct it is equal to another 100~ ap in terms of damage in you poison trail.
skill order: not taking the mega adhesive? that is just pure dumb im sorry to be so brutal, just take a single point in it early game to at least HAVE a cc, in case you are ganked, chasing, or\and exhaust is in cooldown. it can save your life insure a kill save your teammate or initiating ability. i will not upvote this untill you take at least one point into it, otherwise i feel like its mocking my intelligence.
Item Order: this is a mess... the item order itself is okay, but there are just too much **** going on the screen, try to simplify it into a more readable state:
as you can see its much nicer to the eye and its not pointing the already obvious.
also the elixiers and the oracle should be there unless its a single elixier that benefits you specificly in a middle of a build so take them off and put a note on them somewhere in the guide.
Masteries: dude remove the point from ignite and place it in the summoner spell cdr mastery in the utility, 15% less waiting for exhaust and ignite is much better then sometimes having just 10 ap.
Guide: more detailes, bring in some vids if possible of gameplay, explain your role in the team and how do you play, put some situational items in, put situational build in case the whole team is already ap and needs some tank to carry them, add more and more info, this is just not enough to qualify. try to explain why you took this and that, item and rune explanation.
anyway im not going to vote up this guide untill you change some stuff here, since i am afraid it will just be insta-downvoted, +1 rep me if you wish, either way PM me when its changed so ill come and check it out.