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LoL Best Middle Build Guides 2025

Build guides for Middle champions on MOBAFire. Find recommended items and runes by high ranked players to learn the best Middle builds. Create your own champion guide!



2025, Season 2 Guides // Patch 25.11
8.3
66
Votes
9
LoL Champion Zeri Build Guide
LoL Champion Zeri Build Guide

[25.S1.10] Lethality Burst Zeri Mid/Bot Season 15

Guide by RealLrd34 updated May 28, 2025
  • Off-Meta
2025, Season 2 Guides // Patch 25.10
10
4060
Votes
124
LoL Champion Vel'Koz Build Guide
LoL Champion Vel'Koz Build Guide

[Patch 25.10] SEASON 15 Azzapp's Guide To Vel'Koz [MID/APC/SUP]

Guide by Azzapp updated May 27, 2025
  • In-depth
  • Stream
10
90
Votes
3
LoL Champion Azir Build Guide
LoL Champion Azir Build Guide

The Most In-Depth Azir Guide Ever

Guide by Divine Azir updated May 21, 2025
  • In-depth
10
214
Votes
5
LoL Champion Hwei Build Guide
LoL Champion Hwei Build Guide

[25.10] Your True Colors - Complete Hwei Guide

Guide by Soft Headpats updated May 18, 2025
  • In-depth
10
326
Votes
20
LoL Champion Qiyana Build Guide
LoL Champion Qiyana Build Guide

[S15] QIYANA MID GUIDE - YT GUIDES AT END

Guide by Allyooops updated May 17, 2025
  • In-depth
10
31
Votes
0
LoL Champion Syndra Build Guide
LoL Champion Syndra Build Guide

✔️ How to throw Balls

Guide by Fruxo updated May 15, 2025
  • In-depth
10
249
Votes
3
LoL Champion Ahri Build Guide
LoL Champion Ahri Build Guide

✔️ How to use Charm

Guide by Fruxo updated May 15, 2025
  • In-depth
9.8
1277
Votes
51
LoL Champion Akali Build Guide
LoL Champion Akali Build Guide

[25.10] The Ultimate Guide to Akali the Rogue Assassin

Guide by iwontdominatelol updated May 26, 2025
  • In-depth
9.8
187
Votes
16
LoL Champion Zoe Build Guide
LoL Champion Zoe Build Guide

[25.10] clipbot's Zoe guide for beginners

Guide by Aegox updated May 24, 2025
  • In-depth
9.8
1966
Votes
126
LoL Champion Katarina Build Guide
LoL Champion Katarina Build Guide

[25.10] Nyro Challenger Katarina Build Guide

Guide by Nyrolol updated May 20, 2025
9.8
826
Votes
53
LoL Champion Twisted Fate Build Guide
LoL Champion Twisted Fate Build Guide

[25.10] Twisted Fate guide - Grandmaster, Halfhand 🥇

Guide by Halfhand updated May 18, 2025
  • In-depth
9.8
352
Votes
82
LoL Champion Caitlyn Build Guide
LoL Champion Caitlyn Build Guide

❄️🌙🧁Lethality / Burst Caitlyn Mid (+Crit)(+AD Stack)(All Champion Matchups)❄️🌙🧁

Guide by Zero macro updated May 16, 2025
  • In-depth
9.8
485
Votes
35
LoL Champion Lissandra Build Guide
LoL Champion Lissandra Build Guide

🍦 [ 25.10 - SEASON 15 - The MIDLANE ICE QUEEN OF DEATH! 🍦

Guide by RezoneVerified updated May 16, 2025
  • In-depth
9.8
50
Votes
2
LoL Champion Irelia Build Guide
LoL Champion Irelia Build Guide

Blade Dancer Guide (FOR BEGINNERS)

Guide by xumi_k updated May 15, 2025
  • In-depth
9.8
2306
Votes
159
LoL Champion Yasuo Build Guide
LoL Champion Yasuo Build Guide

[15.9] Tempest's Challenger Yasuo Guide [In-Depth]

Guide by WayOfTheTempesst updated May 15, 2025
  • In-depth
9.8
2571
Votes
127
LoL Champion Yone Build Guide
LoL Champion Yone Build Guide

[15.9] Tempest's Challenger Yone Guide [In-Depth]

Guide by WayOfTheTempesst updated May 15, 2025
  • In-depth
9.7
175
Votes
12
LoL Champion Annie Build Guide
LoL Champion Annie Build Guide

[S15] Rank 1 Annie Complete Guide | By Coach xblademojo

Guide by xblademojo updated May 22, 2025
  • In-depth
9.5
68
Votes
3
LoL Champion Veigar Build Guide
LoL Champion Veigar Build Guide

Guide of an Veigar OTP star zall I Challenger Veigar OTP 1217 LP Peak I

Guide by star zall updated May 26, 2025
  • In-depth
9.5
473
Votes
33
LoL Champion Vex Build Guide
LoL Champion Vex Build Guide

Zianni's Vex Guide

Guide by iZianni updated May 24, 2025
  • In-depth
9.5
364
Votes
29
LoL Champion Syndra Build Guide
LoL Champion Syndra Build Guide

Zianni's Syndra Guide

Guide by iZianni updated May 24, 2025
  • In-depth
1 2 3 4 5 6 7 8 29 50
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AatroxAhriAkaliAkshanAlistarAmbessaAmumuAniviaAnnieApheliosAsheAurelion SolAuroraAzirBardBel'VethBlitzcrankBrandBraumBriarCaitlynCamilleCassiopeiaCho'GathCorkiDariusDianaDr. MundoDravenEkkoEliseEvelynnEzrealFiddlesticksFioraFizzGalioGangplankGarenGnarGragasGravesGwenHecarimHeimerdingerHweiIllaoiIreliaIvernJannaJarvan IVJaxJayceJhinJinxK'SanteKai'SaKalistaKarmaKarthusKassadinKatarinaKayleKaynKennenKha'ZixKindredKledKog'MawLeBlancLee SinLeonaLilliaLissandraLucianLuluLuxMalphiteMalzaharMaokaiMaster YiMelMilioMiss FortuneMordekaiserMorganaNaafiriNamiNasusNautilusNeekoNidaleeNilahNocturneNunu & WillumpOlafOriannaOrnnPantheonPoppyPykeQiyanaQuinnRakanRammusRek'SaiRellRenata GlascRenektonRengarRivenRumbleRyzeSamiraSejuaniSennaSeraphineSettShacoShenShyvanaSingedSionSivirSkarnerSmolderSonaSorakaSwainSylasSyndraTahm KenchTaliyahTalonTaricTeemoThreshTristanaTrundleTryndamereTwisted FateTwitchUdyrUrgotVarusVayneVeigarVel'KozVexViViegoViktorVladimirVolibearWarwickWukongXayahXerathXin ZhaoYasuoYoneYorickYuumiZacZedZeriZiggsZileanZoeZyra
Teamfight Tactics Guide