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LoL Best Middle Build Guides 2025

Build guides for Middle champions on MOBAFire. Find recommended items and runes by high ranked players to learn the best Middle builds. Create your own champion guide!



2025, Season 2 Guides // Patch 25.12
10
339
Votes
11
LoL Champion Kayle Build Guide
LoL Champion Kayle Build Guide

Rank 1 EUNE Top 8 EUW I Season 15 Kayle Guide by DesperateNasus Multi-season Challenger

Guide by Desperate Nasus updated June 24, 2025
  • In-depth
10
225
Votes
5
LoL Champion Hwei Build Guide
LoL Champion Hwei Build Guide

[25.12] Your True Colors - Complete Hwei Guide

Guide by Soft Headpats updated June 20, 2025
  • In-depth
10
223
Votes
15
LoL Champion Galio Build Guide
LoL Champion Galio Build Guide

[25.12] Hexeria's detailed Masters Guide to Galio

Guide by Hexeria updated June 16, 2025
  • In-depth
9.8
586
Votes
34
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

💀[NEW SEASON 15] CASSIOPEIA - The POISON Queen of Midlane ☠ 💀

Guide by RezoneVerified updated June 25, 2025
  • In-depth
9.8
4082
Votes
125
LoL Champion Vel'Koz Build Guide
LoL Champion Vel'Koz Build Guide

[Patch 25.12] SEASON 15 Azzapp's Guide To Vel'Koz [MID/APC/SUP]

Guide by Azzapp updated June 24, 2025
  • In-depth
  • Stream
9.8
579
Votes
87
LoL Champion Aatrox Build Guide
LoL Champion Aatrox Build Guide

[15.12] Aatrox Mega Guide 7m MP Master Top 100 worldwide

Guide by Veng Shotz updated June 20, 2025
  • In-depth
9.8
830
Votes
54
LoL Champion Twisted Fate Build Guide
LoL Champion Twisted Fate Build Guide

[25.12] Twisted Fate guide - Grandmaster, Halfhand 🥇

Guide by Halfhand updated June 20, 2025
  • In-depth
9.8
486
Votes
35
LoL Champion Lissandra Build Guide
LoL Champion Lissandra Build Guide

🍦 [ 25.12 - SEASON 15 - The MIDLANE ICE QUEEN OF DEATH! 🍦

Guide by RezoneVerified updated June 17, 2025
  • In-depth
9.8
368
Votes
48
LoL Champion Sylas Build Guide
LoL Champion Sylas Build Guide

[25.12]✨ OTP Sylas MID Guide

Guide by angeLoon updated June 13, 2025
9.8
985
Votes
75
LoL Champion Irelia Build Guide
LoL Champion Irelia Build Guide

(25.11) Eriosun's Master Tier Complete Irelia Guide - Season 15 [UPDATED]

Guide by Eriosunx updated June 12, 2025
  • In-depth
9.7
175
Votes
13
LoL Champion Annie Build Guide
LoL Champion Annie Build Guide

[S15] Rank 1 Annie Complete Guide | By Coach xblademojo

Guide by xblademojo updated June 11, 2025
  • In-depth
9.6
40
Votes
3
LoL Champion Aurora Build Guide
LoL Champion Aurora Build Guide

(25.12) (UPDATED) AURORA GUIDE : Aurora is one of the best champions to OTP right now (MOST MASTERY POINTS EUNE)

Guide by AuroraAddict updated June 22, 2025
  • In-depth
9.5
866
Votes
48
LoL Champion Seraphine Build Guide
LoL Champion Seraphine Build Guide

❤ 🎶 [SEASON 15 NEW - 25.13] MASTER MID Seraphine! SEASON - THE SONG OF DEATH 🎶🎤

Guide by RezoneVerified updated June 25, 2025
  • In-depth
9.5
212
Votes
22
LoL Champion Katarina Build Guide
LoL Champion Katarina Build Guide

[25.13] PrestigeGalaxy's 5M+ Mastery Guide to Katarina! 🗡️

Guide by PrestigeGalaxy updated June 25, 2025
  • In-depth
9.5
980
Votes
77
LoL Champion Kassadin Build Guide
LoL Champion Kassadin Build Guide

[15.12] Rank 1 Kassadin Complete Guide | By Coach xblademojo

Guide by xblademojo updated June 24, 2025
  • In-depth
9.5
53
Votes
3
LoL Champion Irelia Build Guide
LoL Champion Irelia Build Guide

Blade Dancer Guide (FOR BEGINNERS)

Guide by xumi_k updated June 17, 2025
  • In-depth
9.5
345
Votes
29
LoL Champion Malzahar Build Guide
LoL Champion Malzahar Build Guide

[S15] Rank 1 Malzahar Complete Guide | By Coach xblademojo

Guide by xblademojo updated June 17, 2025
  • In-depth
9.5
163
Votes
8
LoL Champion Akali Build Guide
LoL Champion Akali Build Guide

Anguishs GrandMasters Akali Mid/Top S15 Guide Patch [15.12] - Every Matchup/Item/Rune explained!

Guide by Anguish333 updated June 16, 2025
  • In-depth
9.5
190
Votes
17
LoL Champion Zoe Build Guide
LoL Champion Zoe Build Guide

[25.12] clipbot's Zoe guide for beginners

Guide by Aegox updated June 12, 2025
  • In-depth
9.4
111
Votes
14
LoL Champion Talon Build Guide
LoL Champion Talon Build Guide

[25.12] OTP Master Talon Guide with All combos / Season 15

Guide by AmiGo1v9 updated June 13, 2025
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AatroxAhriAkaliAkshanAlistarAmbessaAmumuAniviaAnnieApheliosAsheAurelion SolAuroraAzirBardBel'VethBlitzcrankBrandBraumBriarCaitlynCamilleCassiopeiaCho'GathCorkiDariusDianaDr. MundoDravenEkkoEliseEvelynnEzrealFiddlesticksFioraFizzGalioGangplankGarenGnarGragasGravesGwenHecarimHeimerdingerHweiIllaoiIreliaIvernJannaJarvan IVJaxJayceJhinJinxK'SanteKai'SaKalistaKarmaKarthusKassadinKatarinaKayleKaynKennenKha'ZixKindredKledKog'MawLeBlancLee SinLeonaLilliaLissandraLucianLuluLuxMalphiteMalzaharMaokaiMaster YiMelMilioMiss FortuneMordekaiserMorganaNaafiriNamiNasusNautilusNeekoNidaleeNilahNocturneNunu & WillumpOlafOriannaOrnnPantheonPoppyPykeQiyanaQuinnRakanRammusRek'SaiRellRenata GlascRenektonRengarRivenRumbleRyzeSamiraSejuaniSennaSeraphineSettShacoShenShyvanaSingedSionSivirSkarnerSmolderSonaSorakaSwainSylasSyndraTahm KenchTaliyahTalonTaricTeemoThreshTristanaTrundleTryndamereTwisted FateTwitchUdyrUrgotVarusVayneVeigarVel'KozVexViViegoViktorVladimirVolibearWarwickWukongXayahXerathXin ZhaoYasuoYoneYorickYuumiZacZedZeriZiggsZileanZoeZyra
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