Vladimir guide for MID and TOP, Make this, and you win :)

Make full ap runes for more farm and more hp drain in early game.

With full AP Runes u go need a little defense :)

Well Vlad's passive transform AP to HP and HP to AP ,so u is a off tank AP ,like a Singed ,because this your late game mid is owned, well rylai give you more ap than normal , and warmog give you ap and hp, well spirit visage is very cool for combo with your W, use him in minions for a very cool farm and regen!

Well , ever use your Q for restaure HP, in early game is very cool for stay in your lane, ur E upgrade ur drain (Q) and your W.

For MID or TOP with just one , use this combo E>Q>E>Q And if u go die, ult and later Q. This work more well in tower, when u dont have HP and go recive a dive, stay at the tower waiting, later use E,W,Q,E .Enemy down :)

Pros:
-HP
-Dont have mana
-Cooldown +-
-Hard to die in a gank
...

Cons:
-ur W remove 20% of your HP, if u know plays with him this doesnt import.

Just this, Vladimir is so OP '-'

Well, for farm u just use ur E and later Q, i recommend to use Q in OP Trops :3