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Majorly outmaneuvers you and can utilize her many dashes to avoid your W and escape any dangerous scenario so you will almost never be able to kill her
Yasuo
Can also outmaneuver you with his many dashes and ult blink
Kled
He can utilize his dash to dash through you and avoid your W which is your main source of damage
Darius
You win against him early game which is when he is usually most threatening but be careful mid to lategame against him because if he gets 5 stacks he can 2 shot you
Cho'Gath
Builds Very Tanky which is good for sett because of his true damage and his max hp damage and helps in teamfights because he is easily suplexed into the backline.
Aatrox
Has minor poke damage and has to get close enough to sett to complete a combo and can be obliterated in lane depending on how each player plays
Mordekaiser
its mordekaiser.. plus mordekaiser thrives against immobile champs with no Op passive like darius
Jax
can use his e to dodge setts main source of consistent damage being his auto attacks, and can use his jump to get away from the w or engage when w is on cd
Renekton
Loses hard against sett all game and is out damaged by sett aswell so renek is probably one of setts best matchups
Sion
another beefy boy that can be used against the enemy team with his ult
Illaoi
Can use her e to be able to attack sett from a range and if sett tries to walk up she can deal nearly double damage. and she wins fights if she has her ult and out heals his damage. the only way sett can outplay her is if he ults her right after she ults him.
Ornn
Has a lot of cc but is also very tanky which is good for sett in teamfights.
Dr. Mundo
Beefy boy who is great for sett in teamfights.
Fiora
Annoying *****
Rumble
can use his flamethrower and missiles to poke sett down and before killing him but can be caught out while using his flamethrower and hard lose a trade.
Tryndamere
he can just maul you when he is ulted and can tank through ur true damage with his ult and then just SMACK the **** out of you until you die
Malphite
Relies on his armor passive but just gets true damaged and pooped on
Urgot
can get out damaged because he has very short ranged attacks and is always able to get beaten the **** up by sett
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