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Vayne Build Guide by Panagi23

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League of Legends Build Guide Author Panagi23

The Unkillable Vayne

Panagi23 Last updated on September 11, 2015
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Ability Sequence

Ability Key Q
Ability Key W
Ability Key E
Ability Key R

Not Updated For Current Season

The masteries shown here are not yet updated for the current season, the guide author needs to set up the new masteries. As such, they will be different than the masteries you see in-game.



Offense: 21

Legendary Guardian

Defense: 9


Utility: 0

Threats to Vayne with this build

Show all
Threat Champion Notes
Varus Should i pick Vayne against him:Yes!
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Hello everyone my name is xWilD3MeNx and this is my guide for the Unkillable Vayne!
I 've been playing Vayne for a long time and i think i have the needed experience to make a guide for her.
I am currently platinum 4 and i am working my way up.
Vayne its a lategame beast that if she is played right she can kill the entire enemy team and get out of there alive..She is very mobile and she also have the ability to deal a lot of true damage and be invisible.

So without further ado , lets move on

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  • Late game hyper-carry
  • Highly Mobile
  • High Skill cap
  • High dueling potential allowing exceptional split-pushing
  • True Damage shredder, prevents Vayne from falling off if she gets behind
  • Easier to farm under tower

  • Weak Laning phase
  • Relatively short range (550)
  • Hard to master
  • Easy to get nuked

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Runes & Masteries

Marks:9x Damage
Seals:9x Armor
Glyphs:5x Atack Speed 4x Magic Resist
Quintessences:3x Atack speed

Vayne need the Atack Speed more than anything because she goes well with it.She can proc her Silver Bolts faster..Nothing else to say for the runes..
Masteries are also standard.I pick up Butcher and Feast for sustain.

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Summoner Spells

Standard adc summoner spells

You can also pick up

but i dont recommend it because you are a Vayne

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You always start up with and a .Of course dont forget to buy a .

First Back:

If you have 500- gold buy a .
If you have 800- buy a or and .
If you have 1400- buy a and .
If you have 1400+ buy a

Core Items

Then upgrade your to and your to berserker's boots
When you save up money buy a
Replace with if you are super fed.You can also replace it with a if you want to splitpush faster.
With your core items you will most likely 1v1 everyone in the game if you play correctly.

Continue the build by choosing some of the following items

Nice base damage with lifesteal..With its very good and enemys will have a hard time killing you.I prefer that as a fourth item instead of
Buy it when you want to deal more damage in teamfights..Buying it as a fourth item it can be risky.
Its very good when you have to deal with a fed ap carry for the enemy team or you wanna avoid a skill that might damage you or make you lose the teamfight.
This is an item that i love.Playing as vayne and having some seconds of invisibility its hard for the enemy to hit you with a skill..But if the enemy does then you have this item to save your life.
Its good but i wouldnt build it
I would only build it if i had an enemy that was realy fed
Never build last whisper unless you have a very tanky enemy team or a malphite.Your Silver Bolts do all the job.

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Skill Sequence

At 4 level i rank her Tumble because the 1 less second you get can help you do some plays!Then i continue ranking my Silver Bolts and Final Hour when i am able.After ranking Silver Bolts i start ranking her Tumble.

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Early Gameplay

Playing as Vayne you must be extremely carefully at low levels because thats the point where you are weak..You must focus on farming because her range its not enough to trade with the enemy adc or support.Also dont let the creeps come anywhere near your turret beacuse at low levels Vayne has a hard time farming under tower.

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Mid Gameplay

By this point you may have your and everything begins to be easier for you.You can most likely kill the enemy adc with out having any problems.Also by this point you must have more creeps than the enemy adc and you must farm,farm,farm,splitpush and farm until late game where the action begins.

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Late Gameplay

Lets go wild!With a correct transition from mid game to late , Vayne is ready to deal tons of damage on the enemys and win teamfights that decide the game.Because of her kit Vayne its extremely hard to caught out of position and the enemys have to overcommit to kill her.

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Thank you for reading my guide about Vayne!