Early in the game you'll be looking to make plays in the bot lane using your E Disdain to proc Glacial Augment. At level 1 you can afford to play very aggressively and look to use Flash to force an opponent to eat a bunch of damage from you and your adc or put their flash on cooldown, even if you trade flashes it benefits you in most cases because you still have access to Hextech Flashtraption.
Post level 6 look to use your R Fear Beyond Death to secure kills your adc can't get in lane.

In the mid to late game your primary role is engagement, especially if you can manage to hit Disdain on a high priority target. You want to look to use Turbo Chemtank to get onto the enemy backline when your team can fight, however if you have no problems reaching the enemy backline you can try building Iceborn Gauntlet to further prevent enemy escape or Evenshroud to pump your team's damage. At this point in the game it also becomes much more important to use Fear Beyond Death to secure picks on high priority tagets if possible. You also want to make sure to get a Dead Man's Plate or Force of Nature early into your build to make sure that you can reach targets as the game progresses. Late in the game you can look to purchase Gargoyle Stoneplate and try to make the enemy team focus you with the threat of Fear Beyond Death executing one of their carries.