Click to open network menu
Join or Log In
Mobafire logo - Happy Halloween

Join the leading League of Legends community. Create and share Champion Guides and Builds.

Create an MFN Account


Enter the MOBAFire Ironman and test your skills to compete for the $1,000 USD cash prize and a prestigious award! 🔥

Vayne Build Guide by Jeretar

ADC Unique One Shot Invisible Vayne

ADC Unique One Shot Invisible Vayne

Updated on August 8, 2021
New Guide
Vote Vote
League of Legends Build Guide Author Jeretar Build Guide By Jeretar 2,222 Views 0 Comments
2,222 Views 0 Comments League of Legends Build Guide Author Jeretar Vayne Build Guide By Jeretar Updated on August 8, 2021
Did this guide help you? If so please give them a vote or leave a comment. You can even win prizes by doing so!

You must be logged in to comment. Please login or register.

I liked this Guide
I didn't like this Guide
Commenting is required to vote!
Would you like to add a comment to your vote?

Thank You!

Your votes and comments encourage our guide authors to continue
creating helpful guides for the League of Legends community.


Dark Harvest
Sudden Impact
Eyeball Collection
Ravenous Hunter

Legend: Alacrity
Coup de Grace

+10% Attack Speed
+9 Adaptive (5.4 AD or 9 AP)
+6 Armor


1 2
LoL Summoner Spell: Flash


LoL Summoner Spell: Heal


LeagueSpy Logo
ADC Role
Ranked #8 in
ADC Role
Win 53%
Get More Stats
ADC Role Ranked #8 in
ADC Role
Win 53%
More Vayne Runes

Threats & Synergies

Threats Synergies
Extreme Major Even Minor Tiny
Show All
None Low Ok Strong Ideal
Extreme Threats
Ideal Synergies
Ideal Strong Ok Low None

Champion Build Guide

Unique One Shot Invisible Vayne

By Jeretar
Who Am I?
I am a game lover who still continues his league of legends adventure that I started in 2012. I try to build and develop different structures with the experience I have gained over time.
Why should you choose this item and rune build?
I have experienced that Dark Harvest and Duskblade of Drakthar build work better than other builds. Thanks to this structure, you can inflict tremendous damage to your opponents with the extra attack power that comes when you unlock your ultimate. The advantages of this structure are not only to be able to deal high damage, but by having a low cooldown, you can continuously press your Tumble skill when you unlock your ult and enjoy an adc that is constantly invisible in team battles.
Duskblade of Draktharr works well with Vayne's Tumble and Final Hour abilities. Gives you extra damage, cooldown reduction, and lethality. When you finish this item, you can see how effective you are by opening the ultimate in team battles. This is the most important item of the building.
These are the classic Vayne boots you can see in every Vayne build, the extra attack speed will help you get stronger. Every game should get this boot.
This is the second item you need to buy. The Collector is the second indispensable item in our construction, thanks to its enormous stats and passive.
This item Vayne is in perfect harmony with Tumble, which is extremely important to our construction. The Essence Reaver passive is triggered by attack damage ratio, allowing us to deal incredible damage with the ult and greatly reduce the cooldown.
Now that we have enough critical damage to trigger the Infinity Edge passive, we can take it with peace of mind. This Vayne build is at its strongest Infinity Edge when we run out of gear, you'll be delighted to see your enemies looking for a hole to escape from!
The last item of this build is actually optional. Instead, you are free to choose another item that you think is strong against your opponents for that match. But it still makes me happy to have my last item set to Bloodthirster. Because the extra attack power and lifesteal + shield make me feel safe.

Dark Harvest Vayne is the base rune we will use for our build. When we build this structure that will have high attack power, the damage Dark Harvest will increase in parallel with both the attack power ratio and the soul ratio you collect, and you will be more effective in killing your opponents in team fights.
Sudden Impact Vayne is a perfect match for our build. It gives us extra lethality damage every time we go invisible or use Tumble. This makes it a great match when using Tumble with low cooldowns in teamfights.
I don't have much to say about this rune, enjoy doing more damage by gaining your extra attack power.
This rune gives us the life-stealing feature we use in classic vayne builds. With more attack power and more critical damage, you can drain enormous health.
League of Legends Build Guide Author Jeretar
Jeretar Vayne Guide
Vote Vote
Unique One Shot Invisible Vayne

League of Legends Champions:

Teamfight Tactics Guide