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LoL Best Vayne Build Guides 2025

Build guides for Vayne on MOBAFire. Find recommended items and runes by high ranked players to learn the best Vayne builds. Create your own champion guide!



Season 7 Guides
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Gold Elo Vayne Guide

Guide by littlegosu updated February 22, 2017
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne Guide [7.3] 1M Champion Score (lethality build added)

Guide by mcrehn updated February 10, 2017
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne: The Mechanical God (Patch 6.23)

Guide by Scourge666 updated November 25, 2016
  • In-depth
Season 7 Builds
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

VERSED'S GUIDE TO VAYNE

Build by VersedLeague updated November 5, 2017
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vaxyo's Guids To Vayne

Build by vaxyo updated November 2, 2017
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Be Ready To This Vayne

Build by LetMePrayforBang updated October 28, 2017
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

DUSKBLADE VAYNE BUILD

Build by Opetanyy updated October 25, 2017
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne 1 SHOT / S7

Build by xFreeZ updated October 19, 2017
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne Guide in S7

Build by TraxoPlayZ updated October 8, 2017
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

DOMINATING VAYNE 7.19 (BOT)

Build by Reinoik updated September 28, 2017
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Patch 7.19 brand new vayne build

Build by Lord of Adcs updated September 28, 2017
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne in 7.19

Build by pasang22 updated September 28, 2017
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

[7.19] Vayne, The Night Hunter

Build by NovaMba updated September 27, 2017
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne The Cookie Cutter 7.18 ready for worlds

Build by SkilletRock updated September 21, 2017
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Expermental vayne build

Build by JanisNe updated September 21, 2017
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Experemental Vayne Build

Build by JanisNe updated September 21, 2017
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne Destroyer (Adc 2K17

Build by 50SombrasDeDani updated September 17, 2017
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

New Build Vayne

Build by FranZapa updated September 14, 2017
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Best Vayne Guide Patch 7.18

Build by xxM4rl0nxx updated September 14, 2017
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne hellsing (WIP)

Build by alphybehrendt updated September 11, 2017

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Teamfight Tactics Guide