Best Vayne Build Guides 2025 for LoL Patch 25.17

Rating Pending

vayne
Build by XGenisysX updated May 28, 2025

Rating Pending

VAYNE LETHALITY
Build by szpahel updated May 15, 2025

Rating Pending

Condemned Vayne
Build by Justin Philip Pomaikai La updated April 4, 2025

Off-Meta

7.5

6
Votes
1

S15 VAYNE TOP GUIDE
Build by DANCE762 updated March 5, 2025

Rating Pending

psg vayne art.33
Build by namoradodaluizavendoprens updated February 28, 2025

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REAL DRILL BR VAYNE
Build by namoradodaluizavendoprens updated February 7, 2025

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Vayne Guide
Build by Loue updated January 31, 2025

Rating Pending

Attack Speed Vayne
Build by LionboyLP updated January 28, 2025

Off-Meta

Rating Pending

Hybrid On-Hit Vayne Critical True Damage
Build by CucarachoFeo updated January 16, 2025

Off-Meta

8

8
Votes
1

Ultimate Patch 14.24 Vayne Builds
Guide by mythicdem0n updated December 21, 2024

7.6

17
Votes
6

[14.16] The Ultimate Vayne ADC Guide *updated*
Guide by DJtheTiki updated August 21, 2024

9

11
Votes
0

SOLO CARRY Vayne top lane
Guide by WayB3tterThanYou updated July 16, 2024

7.1

10
Votes
4

Vayne complete guide
Guide by Aleexex updated June 23, 2024

7.4

19
Votes
8

[ 14.12 ] Lethality / AD vayne
Guide by Xr3ad updated June 12, 2024

5.8

7
Votes
6

High Octane Vayne
Guide by Galaxima updated June 4, 2024

In-depth

9.8

858
Votes
71

Vayne, the On-Hit Menace (Patch 14.10)
Guide by ifound1dollar updated May 16, 2024

In-depth

7.3

5
Votes
1

14.10 BROKEN FREE ELO CRITICS VAYNE
Guide by Shoro Mota updated May 24, 2024

Rating Pending

Vayne - for every occasion - by s2 expert
Guide by Oakart updated April 28, 2024

In-depth

10

30
Votes
1

[14.1] [Master] Leaf Vayne Guide - Season 14
Guide by Leaf no Kitsune updated January 15, 2024