Best Vayne Build Guides 2025 for LoL Patch 25.09

9

11
Votes
0

SOLO CARRY Vayne top lane
Guide by WayB3tterThanYou updated July 16, 2024

7.1

10
Votes
4

Vayne complete guide
Guide by Aleexex updated June 23, 2024

7.2

18
Votes
8

[ 14.12 ] Lethality / AD vayne
Guide by Xr3ad updated June 12, 2024

5.8

7
Votes
6

High Octane Vayne
Guide by Galaxima updated June 4, 2024

In-depth

9.8

858
Votes
71

Vayne, the On-Hit Menace (Patch 14.10)
Guide by ifound1dollar updated May 16, 2024

In-depth

7.3

5
Votes
1

14.10 BROKEN FREE ELO CRITICS VAYNE
Guide by Shoro Mota updated May 24, 2024

Rating Pending

Vayne - for every occasion - by s2 expert
Guide by Oakart updated April 28, 2024

In-depth

10

30
Votes
1

[14.1] [Master] Leaf Vayne Guide - Season 14
Guide by Leaf no Kitsune updated January 15, 2024

8.7

9
Votes
0

[14.1b] Mastering Vayne's On-Hit Build for Maximum Impact [READ NOTES]
Guide by Freezeey updated January 19, 2024

Rating Pending

Vayne
Build by Guest updated January 4, 2025

Off-Meta

Rating Pending

VAYNE -> Diamond guide 14.23
Build by Yacynko updated November 25, 2024

Rating Pending

>=====> [14.23] Hentrion's Vayne: Free PDL <=====<
Build by Hentrion updated November 28, 2024

7.3

5
Votes
1

Vayne: Tank Destroyer
Build by Skillcapped69 updated November 12, 2024

Rating Pending

14.22 Vayne ADC
Build by Skillcapped69 updated November 12, 2024

Rating Pending

[Season 14.16] Vayne fast big damage!
Build by ChaseLombre updated October 14, 2024

Rating Pending

op bruiser vayne
Build by doomfallover updated October 3, 2024

Off-Meta

Rating Pending

Vayne Jesuscirraptor ADC The Fast
Build by Jesuscirraptor updated September 22, 2024

Off-Meta

Rating Pending

Vayne Jesuscirraptor SUP
Build by Jesuscirraptor updated August 7, 2024

Off-Meta