Best Vayne Build Guides 2025 for LoL Patch 25.09

Rating Pending

Win every game as a vayne main
Build by Hitsige Henry updated December 30, 2019

Rating Pending

[9.24] Super Saiyan Rosé Vayne - Late Game Beauty Unleashed
Build by KusageRose updated December 23, 2019

Rating Pending

Omni Vayne ~Follow me on Twitch 6N1ghtmare6~
Build by 6N1ghtmare6 updated December 19, 2019

Rating Pending

Critical Vayne Guide
Build by Lee Azrael updated November 29, 2019

Rating Pending

Vayne main : Ez Climb For Season 10
Build by PandaAintBurrito updated November 26, 2019

Rating Pending

Kelly's guide to vayne :)
Build by Yikes12345 updated November 29, 2019

8.3

237
Votes
29

[Top] Hunt Them Down | Vayne
Guide by qasddsa updated September 15, 2019

In-depth

9.8

283
Votes
14

[9.12] Vayne to Diamond
Guide by Uncouthlol updated June 13, 2019

In-depth

Rating Pending

VAYNE ADC 9.10
Guide by DevilsNightMare updated May 28, 2019

Rating Pending

How to Vayne
Guide by wejioads updated May 23, 2019

Rating Pending

Vayne Guide Patch 9.10
Guide by Levi Senpai updated May 17, 2019

Rating Pending

[9.8] Vayne is OP
Guide by DaSticks updated April 17, 2019

7

6
Votes
2

Season 9 [9.7] ADC - It's all gone in Vayne!
Guide by Coraige updated April 9, 2019

Rating Pending

Vayne - The Top Lane Tank's Worst Nightmare
Guide by TSA_Exotic updated February 23, 2019

8.9

41
Votes
4

Why wait for late game? / Hail Of Blades-Nimbus Cloak Vayne
Guide by EvenflowGuides updated February 7, 2019

8.7

23
Votes
4

OG Korean Triple Crit Vayne (1M Mastery)
Guide by B34STLYG4M3R updated February 11, 2019

Rating Pending

God Tier Vayne - FleetFootwork / HailofBlades / DarkHarvest
Guide by TheCoCoFTW updated February 8, 2019

Rating Pending

Vayne Build Platino en Español [9.2]
Guide by Komrad updated January 28, 2019

8.6

27
Votes
5

[9.1] Vayne 9.1 Unexpected Damage
Guide by TwitchTr33Harder updated January 11, 2019