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Vladimir Awsome Build
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Vladimir: your enemies' worst nightmare in mid lane :P
9x Greater Mark of Magic Penetration: The magic penetration you need to pwn your enemy :P
9x Greater Seal of Ability Power,
9x Greater Glyph of Ability Power,
3x Greater Quintessence of Ability Power: the AP you need to put your source active ;)
You can replace Greater Seal of Ability Power for Greater Seal of Health or Greater Quintessence of Ability Power for Greater Quintessence of Health, that's up to you :D
Vladimir is a great begginer, so try to use this for your advantage :D
The points in Utility are quite good; the AP and CDR will help you in Transfusion mostly :D
The points in Offense will give you a boost AP and Magic Penetration.
So I start with Amplifying Tome and an Health Potion. Vlad doesn't have mana, so this items will keep you laning forever. When I can, I buy Hextech Revolver for AP boost and some Spell Vamp; this two bonus will keep your Transfusion relatively annoying <.<'
I don't get Boots too early, because Sanguine Pool will keep yourself safe, but try to get it for some Movement Speed. Don't upgrade this to Ionian Boots of Lucidity; it's more useful getting Will of the Ancients first and then Ionian Boots of Lucidity.
Now it's time to be even more annoying :D Buy Giant's Belt and if you have enough gold get Blasting Wand. AP + HP = HP + AP :P So simple as that. Then finish your Rylai's Crystal Scepter and start making Rabadon's Deathcap. Try to end with a Void Staff or Abyssal Mask.