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Karthus Build Guides, Runes and Items

Karthus The Deathsinger

Find the best Karthus build guides for League of Legends S13 Patch 13.6. The MOBAFire community works hard to keep their LoL builds and guides updated, and will help you craft the best Karthus build for the S13 meta. Learn more about Karthus' abilities, skins, or even ask your own questions to the community!

Season 2 Builds
Rating Pending
LoL Champion Karthus Build Guide
LoL Champion Karthus Build Guide

Karthus Guide to Ownage

Build by cataclysmpg updated July 5, 2012
Rating Pending
LoL Champion Karthus Build Guide
LoL Champion Karthus Build Guide

Karthus, just something to own with

Build by TaleWhip updated July 5, 2012
Rating Pending
LoL Champion Karthus Build Guide
LoL Champion Karthus Build Guide

Death From Above Karthus

Build by Beninobi updated July 5, 2012
Rating Pending
LoL Champion Karthus Build Guide
LoL Champion Karthus Build Guide

Immortal Karthus

Build by rossignoll updated July 4, 2012
Rating Pending
LoL Champion Karthus Build Guide
LoL Champion Karthus Build Guide

Karthus

Build by NA Fukuu updated July 4, 2012
Rating Pending
LoL Champion Karthus Build Guide
LoL Champion Karthus Build Guide

You ain't got luck, time or life on your hands (Karthus)

Build by wacky13 updated July 1, 2012
Rating Pending
LoL Champion Karthus Build Guide
LoL Champion Karthus Build Guide

[LU] Karthus - Silence, i kill you !

Build by TKTheus updated June 30, 2012
Rating Pending
LoL Champion Karthus Build Guide
LoL Champion Karthus Build Guide

boom again a kill

Build by mitriroy updated June 28, 2012
Rating Pending
LoL Champion Karthus Build Guide
LoL Champion Karthus Build Guide

OP GUIDE 1337 BY NAGIBATOR_228

Build by corzjE updated June 27, 2012
Rating Pending
LoL Champion Karthus Build Guide
LoL Champion Karthus Build Guide

Their pain is my pleasure.

Build by gandimeraa updated June 27, 2012
Rating Pending
LoL Champion Karthus Build Guide
LoL Champion Karthus Build Guide

Karthus, the shadow of death! [Br guide]

Build by leobrplayer updated June 26, 2012
Rating Pending
LoL Champion Karthus Build Guide
LoL Champion Karthus Build Guide

lolol

Build by Guest updated June 24, 2012
Rating Pending
LoL Champion Karthus Build Guide
LoL Champion Karthus Build Guide

Spell Vamp Cool Down Magic Pen Karthus

Build by Guest updated June 23, 2012
Rating Pending
LoL Champion Karthus Build Guide
LoL Champion Karthus Build Guide

Karthus Build

Build by Benokojo updated June 21, 2012
Rating Pending
LoL Champion Karthus Build Guide
LoL Champion Karthus Build Guide

Karthus - I cant Die

Build by takicha99 updated June 21, 2012
Rating Pending
LoL Champion Karthus Build Guide
LoL Champion Karthus Build Guide

Karthus the Devil of Mid

Build by Ferat updated June 13, 2012
Rating Pending
LoL Champion Karthus Build Guide
LoL Champion Karthus Build Guide

vs patk / matk / mix

Build by TQMMY updated June 12, 2012
Rating Pending
LoL Champion Karthus Build Guide
LoL Champion Karthus Build Guide

A Pros Guide to Karthus

Build by Kaldra117 updated June 9, 2012
Rating Pending
LoL Champion Karthus Build Guide
LoL Champion Karthus Build Guide

| Karthus - For The Unliving |

Build by Guest updated June 8, 2012
Rating Pending
LoL Champion Karthus Build Guide
LoL Champion Karthus Build Guide

Karthus Equipment

Build by lDreiKl updated June 7, 2012
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Karthus Build & Runes

If you're looking for the best rune build for Karthus we've got you covered. Below you can find the best items and runes to build for Karthus, as determined by calculations of thousands of Plat+ League of Legends games. If you are already familiar with how to play Karthus this is a great resource to quickly get a good rune selection for Patch 13.6. However, if you are a new Karthus player we highly recommend reading through some of the guides above to learn why this build is strong on Karthus!

Patch 13.6: 2106413 matches scanned * Each section of the build is rated independently of the others

Karthus's Runes

Karthus's Best Runes 50%

Win Rate 14068 Games

  • 1
  • 2
  • 3
Domination
LoL Path: Domination
LoL Rune: Dark Harvest
Dark Harvest
LoL Rune: Cheap Shot
Cheap Shot
LoL Rune: Eyeball Collection
Eyeball Collection
LoL Rune: Treasure Hunter
Treasure Hunter

Precision
LoL Path: Precision
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Coup de Grace
Coup de Grace

Second Best

Karthus's 2nd Best Runes 49%

Win Rate 3851 Games

Inspiration
LoL Path: Inspiration
LoL Rune: First Strike
First Strike
LoL Rune: Magical Footwear
Magical Footwear
LoL Rune: Future's Market
Future's Market
LoL Rune: Cosmic Insight
Cosmic Insight

Domination
LoL Path: Domination
LoL Rune: Ultimate Hunter
Ultimate Hunter
LoL Rune: Eyeball Collection
Eyeball Collection

Third Best

Karthus's 3rd Best Runes 56%

Win Rate 2460 Games

Domination
LoL Path: Domination
LoL Rune: Dark Harvest
Dark Harvest
LoL Rune: Cheap Shot
Cheap Shot
LoL Rune: Eyeball Collection
Eyeball Collection
LoL Rune: Treasure Hunter
Treasure Hunter

Precision
LoL Path: Precision
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Last Stand
Last Stand

Karthus's Summoner Spells

Karthus's Best Summoner Spells 51%

Win Rate 21119 Games

  • 1
  • 2
  • 3

Second Best

Karthus's 2nd Best Summoner Spells 49%

Win Rate 14544 Games

Flash Smite

Third Best

Karthus's 3rd Best Summoner Spells 45%

Win Rate 148 Games

Ghost Smite

Karthus's Starters

Karthus's Best Starter Items 50%

Win Rate 12394 Games

  • 1
  • 2
  • 3

Trinket

Karthus's Best Trinket 50%

Win Rate 27704 Games

  • 1
  • 2
  • 3

Second Best

Karthus's 2nd Best Trinket 45%

Win Rate 5613 Games

Stealth Ward

Third Best

Karthus's 3rd Best Trinket 89%

Win Rate 291 Games

Eye of the Herald
Don’t forget
to Buy Wards

Karthus's Ability Order

Karthus's Best Ability Order 65%

Win Rate 16006 Games

  • 1
  • 2
  • 3
Patch 13.6: 2106421 matches scanned * Each section of the build is rated independently of the others

Karthus's Runes

Karthus's Best Runes 56%

Win Rate 3439 Games

  • 1
  • 2
  • 3
Domination
LoL Path: Domination
LoL Rune: Dark Harvest
Dark Harvest
LoL Rune: Taste of Blood
Taste of Blood
LoL Rune: Eyeball Collection
Eyeball Collection
LoL Rune: Ultimate Hunter
Ultimate Hunter

Precision
LoL Path: Precision
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Last Stand
Last Stand

Second Best

Karthus's 2nd Best Runes 56%

Win Rate 1476 Games

Domination
LoL Path: Domination
LoL Rune: Dark Harvest
Dark Harvest
LoL Rune: Cheap Shot
Cheap Shot
LoL Rune: Eyeball Collection
Eyeball Collection
LoL Rune: Ultimate Hunter
Ultimate Hunter

Precision
LoL Path: Precision
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Last Stand
Last Stand

Third Best

Karthus's 3rd Best Runes 63%

Win Rate 119 Games

Domination
LoL Path: Domination
LoL Rune: Dark Harvest
Dark Harvest
LoL Rune: Cheap Shot
Cheap Shot
LoL Rune: Eyeball Collection
Eyeball Collection
LoL Rune: Treasure Hunter
Treasure Hunter

Precision
LoL Path: Precision
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Last Stand
Last Stand

Karthus's Summoner Spells

Karthus's Best Summoner Spells 55%

Win Rate 7435 Games

  • 1
  • 2
  • 3

Second Best

Karthus's 2nd Best Summoner Spells 58%

Win Rate 91 Games

Exhaust Teleport

Third Best

Karthus's 3rd Best Summoner Spells 52%

Win Rate 519 Games

Flash Teleport

Karthus's Starters

Karthus's Best Starter Items 55%

Win Rate 14490 Games

Trinket

Karthus's Best Trinket 58%

Win Rate 4900 Games

  • 1
  • 2
  • 3

Second Best

Karthus's 2nd Best Trinket 50%

Win Rate 3225 Games

Stealth Ward

Third Best

Karthus's 3rd Best Trinket 55%

Win Rate 379 Games

Oracle Lens
Don’t forget
to Buy Wards

Karthus's Ability Order

Karthus's Best Ability Order 65%

Win Rate 1149 Games

  • 1
  • 2
  • 3
Patch 13.6: 2106417 matches scanned * Each section of the build is rated independently of the others

Karthus's Runes

Karthus's Best Runes 61%

Win Rate 123 Games

  • 1
  • 2
  • 3
Domination
LoL Path: Domination
LoL Rune: Dark Harvest
Dark Harvest
LoL Rune: Cheap Shot
Cheap Shot
LoL Rune: Eyeball Collection
Eyeball Collection
LoL Rune: Ultimate Hunter
Ultimate Hunter

Precision
LoL Path: Precision
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Last Stand
Last Stand

Second Best

Karthus's 2nd Best Runes 58%

Win Rate 100 Games

Domination
LoL Path: Domination
LoL Rune: Dark Harvest
Dark Harvest
LoL Rune: Cheap Shot
Cheap Shot
LoL Rune: Eyeball Collection
Eyeball Collection
LoL Rune: Ultimate Hunter
Ultimate Hunter

Precision
LoL Path: Precision
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Coup de Grace
Coup de Grace

Third Best

Karthus's 3rd Best Runes 55%

Win Rate 218 Games

Domination
LoL Path: Domination
LoL Rune: Dark Harvest
Dark Harvest
LoL Rune: Taste of Blood
Taste of Blood
LoL Rune: Eyeball Collection
Eyeball Collection
LoL Rune: Ultimate Hunter
Ultimate Hunter

Precision
LoL Path: Precision
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Last Stand
Last Stand

Karthus's Summoner Spells

Karthus's Best Summoner Spells 50%

Win Rate 2064 Games

  • 1
  • 2
  • 3

Second Best

Karthus's 2nd Best Summoner Spells 48%

Win Rate 2109 Games

Flash Teleport

Third Best

Karthus's 3rd Best Summoner Spells 60%

Win Rate 52 Games

Exhaust Ignite

Karthus's Starters

Karthus's Best Starter Items 50%

Win Rate 8692 Games

  • 1
  • 2

Trinket

Karthus's Best Trinket 52%

Win Rate 2082 Games

  • 1
  • 2
  • 3

Second Best

Karthus's 2nd Best Trinket 47%

Win Rate 2326 Games

Stealth Ward

Third Best

Karthus's 3rd Best Trinket 51%

Win Rate 473 Games

Oracle Lens
Don’t forget
to Buy Wards

Karthus's Ability Order

Karthus's Best Ability Order 60%

Win Rate 1387 Games

  • 1
  • 2
  • 3

Karthus Counters

Learn Karthus' counters and discover matchups where they have an advantage! When you're starting a game of League of Legends you should always keep in mind if you'll be at an advantage or disadvantage against your opponent, so you can know whether to bully them or play safe. You can find detailed breakdowns of each matchup on CounterStats, and you can also check out some Karthus guides to see how to build and play against other champions you may find yourself up against!


This counter data is for Karthus Jungle in Plat+ games. The percent shown is the enemy champion's counter rating against Karthus. Counter rating is our own statistic that factors in counter kills, overall kills, early lead ratio, comeback ratio, and win percent to give the whole picture of that champion's effectiveness as a counter pick.

Karthus Skins

Karthus' Abilities

Questions About Karthus

League of Legends Champions:

Teamfight Tactics Guide