If you start D shield, hold on to grey health for as long as possible before you regen as D shield heals you for missing health.

E start with HoB is good cheese vs. champs who have a bad level 1.

Pyke has the highest base armor in the game - if you're vs. a scaling ad champ mid but the rest of the enemy team is ap, it may be worth to pick mr runes.

It's easy to bait a roam towards bot, then W and go top. Enemy laner will spam ping bot and then you'll appear top.

You can ignite mid-R animation if the enemy is 1hp above the R threshold.

Zac's passive blobs are coded as minions, if you R them your R will not reset.

R does true damage through shields.

Advantages

Arguably best roams in the game.

Has two get-out-of-jail-free cards (W and E).

R passive makes missing creeps mid worth.

Good gank set-up, especially with an early game jungler.

Very strong map presence due to move speed.

Very strong mid-game.

Super fun.

Disadvantages

Weak waveclear pre-tiamat.

Weak waveclear post-tiamat.

Feast or famine champ.

Weak late-game.

Can't build HP to go tanky if you fall behind and want to tank for your ADC.

Can be poked out and shoved under tower easily early game.

If you miss your R reset you can throw a teamfight.

Stopwatch counters you.

Healers counter you.