Well as far as I know there are more then a couple who can such as Ez akali Kat Kayle ect...
But I feel that most are better off going all atk dmg or full ap. so I don't know why but I really want to see hybrids using combinations of atk dmg and ap or ap and atk speed or what ever it magi hit be. So I really don't know enough about making these guides as I am a horrible teacher but what I would like to do is continue making hybrid builds with the hopes that you the public will see them and mess around with them possibly finding a better build and hopefully promote the use of more in game hybrids or even get riot to think about different runes or masteries to more so benefit hybrid characters in future seasons other then the hybrid pen witch I think I'm the only person on earth who uses them for mostly obvious reasons.
Well as far as Ez goes I think he make for a mean hybrid but don't know if it holds up end game of course I'm still messing around with builds for him. Ummmmmmmmmmmmmmmmmmmmmmm I really don't know what els to say now besides ya make a hybrid build. And don't ever underestimate Kayle atk spd and ap.