When laning against champions like Teemo and Kayle, always make sure passive is up if you're close to half and plan on staying in lane. When fighting someone like that, try to bait them into falling for your knock-up, or E ability. Once you do that, hit them with a W then a Q. That should be a large chunk of their health. Then just keep poking them down while gaining health back from your blobs and keeping in mind whether or not you have passive. If you have passive up, do not be afraid of dying because chances are you'll deal a large amount of damage enough to cause a disengage from the opponent and if not, then you can always just back off after dealing the damage. ***ZAC TOP IS SO MUCH FUN IF PLAYED RIGHT*

If caught in a tough situation, two possible ways to get out by yourself are to Ult or to E out. Another way could be to flash, but normally there would be no need to do so. When using E to escape, make sure there is no cc to stop you from charging up and launching yourself far.