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Be careful as his R can burst you and your adc, and if besides that he uses his Q on you, you might have to choose between saving you or your carry.
Nocturne
Rammus
If he engages your carry, the enemy team is most likely to kill him no matter what you do.
Wukong
Darius
Not a problem if you have a good positioning.
Yasuo
His R and W are annoying.
Thresh
Katarina
Kog'Maw
High DPS champion. Kayle's R will give it enough time alive to clean any threat, while her Q will help him chase running enemies. Besides, Kayle has a nice synergy with pretty much any DPS champion.
Xayah
DPS champion. If Kayle plays carefully, Xayah will have 2 high peel abilities that allow her to burst kind of as much as she wants to. Besides, she can peel Kayle a bit using her E.
Twitch
DPS champion.
Azir
DPS champion. Besides, can peel Kayle using his R.
Yasuo
DPS champion. Besides, he peels Kayle when he ults.
Cassiopeia
DPS champion.
Tristana
High DPS champion. Besides, can peel Kayle using her R.
Kalista
DPS champion. Besides, can peel Kayle using her R.
Vayne
DPS champion. Despite, can barely peel Kayle.
Varus
DPS champion. Besides, can peel Kayle using his R.
Talon
Kayle can give him the sustain he needs to full-combo more than one person. Besides, she can ult him if needed when he doesn't have his R.
Twisted Fate
If ADC: DPS champion. Besides, can peel Kayle a bit using his stunt.
Master Yi
High DPS champion.
Draven
High DPS champion. His E won't peel Kayle too much.
Sivir
DPS champion. Besides, can peel Kayle using his R.
Jinx
High DPS champion. Besides, can peel Kayle a bit using her E.
Jax
DPS champion.
Kai'Sa
DPS champion.
Karthus
DPS champion. Besides, can peel Kayle using his wall.
Kindred
DPS champion. Besides, can peel Kayle using his R.
Synergies
IdealStrongOkLowNone
Kog'Maw
High DPS champion. Kayle's R will give it enough time alive to clean any threat, while her Q will help him chase running enemies. Besides, Kayle has a nice synergy with pretty much any DPS champion.
Xayah
DPS champion. If Kayle plays carefully, Xayah will have 2 high peel abilities that allow her to burst kind of as much as she wants to. Besides, she can peel Kayle a bit using her E.
Twitch
DPS champion.
Azir
DPS champion. Besides, can peel Kayle using his R.
Yasuo
DPS champion. Besides, he peels Kayle when he ults.
Cassiopeia
DPS champion.
Tristana
High DPS champion. Besides, can peel Kayle using her R.
Kalista
DPS champion. Besides, can peel Kayle using her R.
Vayne
DPS champion. Despite, can barely peel Kayle.
Varus
DPS champion. Besides, can peel Kayle using his R.
Talon
Kayle can give him the sustain he needs to full-combo more than one person. Besides, she can ult him if needed when he doesn't have his R.
Twisted Fate
If ADC: DPS champion. Besides, can peel Kayle a bit using his stunt.
Master Yi
High DPS champion.
Draven
High DPS champion. His E won't peel Kayle too much.
Sivir
DPS champion. Besides, can peel Kayle using his R.
Jinx
High DPS champion. Besides, can peel Kayle a bit using her E.
Jax
DPS champion.
Kai'Sa
DPS champion.
Karthus
DPS champion. Besides, can peel Kayle using his wall.
Kindred
DPS champion. Besides, can peel Kayle using his R.
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