Remember it takes 3 ability hits to set up your passive. You will see a red triangle around your enemy when its ready and it takes an auto attack to proc it, the damage it does is normally 1.5x that of your ad. This combined with ignite makes it almost impossible for enemies to escape you in a 1v1. (early game kill pressure) Some short and quick combos for early game would be w then ranged q to drag your second w back to set up your passive which you can then proc immediately and ignite, a lot of times this will kill your enemy early game at level 2. Another example is w, flash, melee q, which will also proc your passive and you get melee q damage however this is a waste of a flash and a lot better for electrocute builds. If I manage to kill the enemy early game and get ironspike before level 6 then I would use ranged q, w, and ironspike whip and stick on them until my second w hits and i get my passive. If you have the upper hand, you will win and not only will this mentally scar your opponent into playing safer but it allows you to push your lane harder until level 6 which you can then gank a lot more frequently. A full combo would normally be e over wall, w, ranged q, and then cast r depending on where they are. If I'm not full hp I would cast it the moment i finish my ranged q animation to get healed and to give me time to choose the best target of all of them. I would then follow this up with gore drinker if I'm below 60% hp, proc passive on my current target and then switch targets which I would then shoot a melee q, then ignite and switch targets again. This allows for a constant rotation between rake and diplomacy and you can get 2-3 kills easily if you are fed that is. This is the basic full combo. Asides from that there isn't much else to say. Ranged q is good for pursuit or escape by dashing to a minion, w is good for slowing running targets because on second hit it slows them, and e is good for both engage/escape. R is also good for escape or diving under tower for movement speed.