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Karthus Build Guide by Aenimatora

Middle The Deathsingers Wake - A Karthus Guide

Middle The Deathsingers Wake - A Karthus Guide

Updated on August 1, 2022
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League of Legends Build Guide Author Aenimatora Build Guide By Aenimatora 4,700 Views 0 Comments
4,700 Views 0 Comments League of Legends Build Guide Author Aenimatora Karthus Build Guide By Aenimatora Updated on August 1, 2022
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Runes: Total Destruction

1 2
Dark Harvest
Taste of Blood
Eyeball Collection
Ultimate Hunter

Presence of Mind
Last Stand

+9 Adaptive (5.4 AD or 9 AP)
+9 Adaptive (5.4 AD or 9 AP)
+8 Magic Resist


1 2 3 4
Standard Summoners
LoL Summoner Spell: Chilling Smite

Chilling Smite

LoL Summoner Spell: Flash


Ability Order Standard Skillorder for every Lane

Threats & Synergies

Threats Synergies
Extreme Major Even Minor Tiny
Show All
None Low Ok Strong Ideal
Extreme Threats
Ideal Synergies
Ideal Strong Ok Low None


Hi, my name is Aenimatora.

For years i played with several Accounts in higher Elos and on my main mostly between G1 and Platinum 1. I am sadly mostly inactive now, but i use to play still one of my most beloved Mains: Karthus. For 11 years he is my most beloved champ to play. This guide should help you to understand why.
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Pros / Cons


- Best farmer in the whole game. Has insane wave- and jungleclear

- The ultimate Lategame AP. He becomes the longer the game goes kind of an unbeatable demigod facerolling all of the enemyteam

- Can all in most champs easy in early state of the game if you are good enough with the Lay waste

- A global Nuke which damages all regardless where they are

- Insanely good in securing and stealing objectives

- The passive is godlike vs engage comps !

- High Snowballpotential

- 10 kills on him pre Minute 30 and the enemy team will surrender

- When Karthus dies...he doesn´t die. Or does ? Nobody knows. But the passive is awesome !


- Extremly High Skillcap and with it hard to master

- Very squishy

- No mobility and escape.

- Vulnerable to ganks and counterjungling if played too aggressive and not wise

- Incredible difficult to use him effectivly in teamfights. Timing and positioning required

- Not the best poke vs siege comps
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Jungle Pathing

To clear your camps as fast as you can is super important. Watch this Video to understand why this is so imporant !
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Laning at Midlane

Regardless of the matchup your lay waste is the greatest farming spell in the whole game. You can easily play aggressive, or farm under turret. Analyze the matchup and watchout which items to buy. Karthus is in any matchup very effective and good.
League of Legends Build Guide Author Aenimatora
Aenimatora Karthus Guide
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The Deathsingers Wake - A Karthus Guide

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