Cassiopeia Build Guide by demonlordraiden
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Ability Sequence
Not Updated For Current Season
The masteries shown here are not yet updated for the current season, the guide author needs to set up the new masteries. As such, they will be different than the masteries you see in-game.
Masteries
I. Introduction
Welcome back, Mobafire! I am Demonlordraiden, author of Lulu, the Fae Machinegun and I welcome you to my newest build!
I.I. Build Summary
Firstly, a short video to describe this build.
Above was Samuel L. Jackson, one of the best actors ever to walk the earth. The movie, Snakes on a Plane. While this quote was
OBVIOUSLY not written about 
Cassiopeia or this build, it fits very well.
"I have had it with these mother f*cking snakes, on this mother f*cking plane."
Now, if you would, replace "these" with "this," "snakes" with "snake," and "on this mother f*cking plane" to "in this mother f*cking lane."
That's right, "I have had it with this mother f*cking snake, in this mother f*cking lane." Describes this build well.
Cassiopeia is a very powerful Damage Over Time Champion, utilizing Noxious Blast, Miasma, and 
Ignite to damage enemies while out of sight, but not out of mind.
I.II. Pro/Con
Pro:
Damage Over Time out the Roof!!
Rarely Mana Hungry
Very Low Cooldowns
Con:
Squishy
Very Low Crowd Control
II. Pre-Game Preparation
Like any other champion, Cassiopeia needs Pre-Game Preparation to be truly useful. Unlink the previous champion I built (
Lulu), Cassiopeia has very few viable builds. Ability Power is where it's at.
Why?
Her Damage Over Time scales off of her Ability Power.
Enough Said.
II.I. Masteries
Cassiopeia's Mastery Page is a standard Ability Power build, with some extra Utility.
II.I.I. Offense
Summoner's Wrath
is just amazing here. Why? It buffs Ignite, and Ignite equals more Damage Over Time.
Mental Force
effects my Ability Power, increasing my Poison Damage. See a pattern here?
Sorcery
helps with the almost nonexistent Cooldowns, but also allows for
Arcane Knowledge
.
Arcane Knowledge
increases Cassiopeia's Magic Penetration, leading to, wait for it...MORE POISON DAMAGE.
Havoc
is...well...similar to above. Damage works with Poison.
Blast
...well...do I even need to explain this?
Archmage
...
Executioner
is greatness because of two reasons. One, it helps on enemy Champions. Two, it helps on Monsters.
II.I.II. Defense
I have no Defense Masteries (again).
II.I.III. Utility
Expanded Mind
makes it where I'm less likely to be Mana Hungry.
Improved Recall
helps keep zero deaths, as we can teleport out if there is a problem.
Meditation
is nice during prolonged fights to help with Noxious Blast's constant spamming.
Scout
helps keep the jungle secure.
Runic Affinity
is a MUST HAVE for any Jungler, including Cassiopeia.
II.II. Runes
Cassiopeia has very similar runes to a normal 
Brand or 
Veigar, going for high Ability Power.
II.II.I. Glyphs
Greater Glyph of Ability Power increases Ability Power. Why would we do that? If you answered with, "to deal more Poison Damage," you were right!
II.II.III. Quintessences
Greater Quintessence of Gold helps with Early Game Items.
Greater Quintessence of Scaling Ability Power is for what? What? WHAT!!??
...I'm sorry for yelling :( Can you forgive me? Thank you friend :)
II.III. Summoner Spells
Ignite is a MUST HAVE. MUST...HAVE...Extra Damage Over Time is a godsend for Cassiopeia.
Flash is just perfect on Cassiopeia, since, aside from an effect on Noxious Blast (and that involves a Skill Shot in a Sticky Situation), has no Escape Mechanism. Flash fixes that.
III. In Game, Part I: Basic Information
Time for the fighting, but what do we do first? Run for a lane? Go mid? Die?
NO!
Follow this guide, breathe slowly, and mastery of Cassiopeia will be yours.
III.I. Abilities
Poison?
Poison.
Poison?
Poison.
III.I.I. Level Order
Go for Noxious Blast, then Twin Fang, followed by Noxious Blast and Miasma. Then, go for another Noxious Blast and Petrifying Gaze. Then go for what you see fit. I usually go in the "pattern" seen above.
III.II.I. Build Order
Follow the order at the top. Sorcerer's Boots, 
Doran's Ring (two), 
Rod of Ages, and 
Rabadon's Deathcap (two).
III.II.II. Justification(s)
Sorcerer's Boots increase Movement Speed and Magic Penetration.
Doran's Ring help with early game Mana and Health.
Rod of Ages is best grabbed early, as to utilize it's "upon leveling" bonus.
Rabadon's Deathcap is god. Enough said. The Ability Power is Insane!
IV. In Game, Part II: Strategy
Battle Plans, Strategy, Tactic, Teamwork, etc.
IV.I. Advanced Strategies, Solo
Plans to utilize while alone. I believe that Cassiopeia is best used solo, but that's just my opinion.
IV.I.I. Hybrid
Fololow IV.I.II. Jungle, Gank, IV.I.III. Jungle, Monsters and IV.I.IV. Laning to successfully mix and master all three of Cassiopeia's most viable builds.
IV.I.II. Jungle, Gank
Cassiopeia is unstoppable as a ganking machine.
Noxious Blast and/or Miasma to set up Poison and gain the Movement Boost, then Ignite and/or Twin Fang to add more Damage Over Time and deal desirable Burst Damage. If you can, Gank multiple Champions with Petrifying Gaze, then repeat from the top.
IV.I.III. Jungle, Monsters
Cassiopeia also pack a mean punch against Monsters.
Follow the Ganking Strategies, but on Monsters. Around Level 16 or so, you can solo the Dragon (funny, so rare for a Caster to go for the Jungle, especially Dragon, but both of mine specialize in it)
IV.I.IV. Laning
Laning is also a piece of cake with Cassiopeia.
Noxious Blast and Miasma have nice Areas of Effect for Minion fodder, while Minion Cover and Turrets defend you very well from other Champions.
IV.II. Advanced Strategies, Team
Strategies to be used when other players are around.
IV.II.I. Geometric Hell, with Singed
Cassiopeia is unique in the fact that she is the only Champion who can utilize the Abilities of other Champion. Specifically, Poison.
Singed's 
Poison Trail allows Cassiopeia's Twin Fangs to use their Cooldown Bonus.
Geometric Hell is basically large pools of Noxious Blast, Miasma, Poison Trail, and 
Mega Adhesive.
IV.II.II. Poison Jungle, with Teemo
Teemo is one of the four Champions with Poison.
If you take advantage of his stealth ( Camouflage) and Poison (
Toxic Shot and 
Noxious Trap) with Cassiopeia's Noxious Blast and Miasma to set up a Jungle (or bush) of Poison. Bonus points for an offscreen kill :D
IV.II.III. The Bubonic Plague, with Twitch
Oh Gods...
Twitch can be utilized with his stealth with 
Ambush and Ranged, Quick to Spread Poisons with 
Deadly Venom, Ambush, and 
Spray and Pray.
Cassiopeia can be utilized with her Ranged Poisons and Area of Effect Poisons with Noxious Blast and Miasma, along with her Stun with Petrifying Gaze.
Mix the Area Damage and the Pinpointed Damage, and you have a splash of Poisony epicness.
I have tried this multiple times and succeeded well, as well as with Teemo.
Now, I won't write it because it's rare and just a mix, but with Cassiopeia, Teemo, AND Twitch, the team is just Over Powered. Now imagine that, with Singed.
Poisongasm.
That just happened.
V. Conclusion
In conclusion, Cassiopeia is an extremely viable Champion, and one of (if not THE) most powerful Damage Over Time Champion.
Cassiopeia is amazingly used in the Jungle, Lanes, or on teams with anyone, especially Singed, Teemo, and/or Twitch
Thank you for reading thus far, and have a good time playing!
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