Summon Voidling
On every fourth ability use, Malzahar summons a Voidling that remains on the field until it is killed or 21 seconds have passed. If Malzahar dies, the Voidling stays behind but stops attacking.
Voidlings grow in size after 7 seconds, gaining 50% bonus attack damage and armor, and frenzy after 14 seconds, gaining 100% bonus attack speed. It is important to mention that voidlings do not attack just because they want. They prioritize the following targets:

+Targets affected by Nether Grasp
+Targets affected by Malefic Visions
+Targets attacked by Malzahar

A good use of this passive will help you block most of the damage/CC caused by skillshot-based champions! Make champions like or suffer!

Call of the Void
Malzahar summons two orbs at the target location perpendicular to which way he is facing after a 0.5-second delay, dealing magic damage to all enemies caught between the orbs and silencing them. This pretty nice skillshot is one of the few (and longest) silences in the game. However, and unlike other silences in the game (hello and ) it is hard to land it, and also has casting time, thus giving enemies with high mobility enough time to get away. It is more easy to land this skill in teamfights than in laning phase. Use it wisely.
Pro tip: When the game starts, put one point in Call of the Void and cast it three times in base, so that you have a voidling ready to summon in lane.

Null Zone
ACTIVE: Malzahar creates a zone of negative energy for 5 seconds, dealing magic damage every second to all enemies standing on it, capped at 120 against minions and monsters. This is a beautiful skill that you won't be using much in laning phase unless you perform your combo on your enemy, and this is also the last skill you'll want to max. But in late game this skill appears, and then is when the magic occurs.

Null zone deals: 4 / 5 / 6 / 7 / 8% (+ 1% per 100 AP) magical damage of target's maximum health PER SECOND . I will do the maths for you: you find a with 4000 hp, and you have 500 AP. 8% of Null zone + 5 coming from your ap means that you will shred 13% of his maximum health per second That is to say, if you manage to get him standing on your W for 4 seconds, you will have dealt 2080 damage (MR apart). Insane.

Malefic VisionsACTIVE: Malzahar infects the target enemy's mind, dealing them magic damage every half second over 4 seconds.
If the target dies during this time, they pass Malefic Visions onto the closest enemy, refreshing the duration and restoring a portion of Malzahar's mana. This is the ability that distinguishes Malzahar. Also known by many flamers as "the ebola" this skill tends to be pretty annoying, because once the ability gets to take 60% of a minion's health, it farms alone. You can go and ward the bushes, the ability will get the cs for you. However, it is important to know when to use it. For example, you put one point in E at level 2 and immediately cast it on a minion. Was it effective? No, because you probably didn't kill that minion, and even if you did, you won't be able to kill the following one. Use your E to farm once you have some points on it, or you'll waste your mana.

Nether Grasp
Malzahar knocks down the target enemy champion and channels for up to 2.5 seconds, suppressing them and dealing them magic damage every half second while the channel holds.
This is your can't-go-wrong skill during laning phase. It is the lockdown to your combo and leaves defenseless every champion (or well, almost every champion ...).
If you manage to ult someone in a teamfight, and you're good positioned, it is a safe kill to your team. But if you're mispositioned, you'll end up dying, since you can't move while channeling, and most probably won't kill who you wanted to kill. Remember to not ult champions with or .
This skill has an excellent synergy with since you can cast it while you're ulting! BUUUUUUUUUUUUT↓

IMPORTANT:
If you're going to cast Nether Grasp at full range DO NOT TRY TO IGNITE WHILE ULTING, OR YOU'LL CANCEL IT.
Whereas Nether grasp's range is 700, Ignite's range is 600. Remember this when you're ulting.