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Runes:
+10% Attack Speed
+9 Adaptive (5.4 AD or 9 AP)
+6 Armor
Spells:
Flash
Heal
Items
Ability Order Skills
Night Hunter (PASSIVE)
Vayne Passive Ability
Threats & Synergies
Draven
If you're playing against him, avoid any kind of battles - fast trades are not worth, as the same as going in. The only way to win against him is stunning him by your E, then attacking him. If support would stun him too - that should be kill. If Draven will play agro and won't let you farm - you should wait till your jungler's gank.
Lulu
Prob the best support to play with on Vayne. Has shield, slow, +speed, polymorph and her ultimate heals you and knocks up enemies. If you're well coordinated with your Lulu, you can do R + Q, then goes into enemy -> Lulu ults you and enemies are knocked up. If you would make it with your support, it's easy lane.
Lulu
Prob the best support to play with on Vayne. Has shield, slow, +speed, polymorph and her ultimate heals you and knocks up enemies. If you're well coordinated with your Lulu, you can do R + Q, then goes into enemy -> Lulu ults you and enemies are knocked up. If you would make it with your support, it's easy lane.
Champion Build Guide
Advantages and disadvantages of Vayne
Advantages: +A monster in late game +Good mobility with her ![]() +May stun with her ![]() +May be invisible with her ![]() +A LOT of true damage with her ![]() |
Disadvantages: -Seriously bad early game -Low ranged -Requires good farm in her early game -Squishy -Takes a lot of time to master her |
Build, Runes, Abilities
1. ITEMS
Starter item
That's actually pretty simple. When you're against poke lane (example:




- 1ST ITEM:
Definitly

- BOOTS
There are only 3 kind of boots that is worth to build on

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- CORE ITEMS
After we build

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If enemy has a lot of AP Champs you can build


- NEXT ITEMS
Here are some other items:
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2. RUNES
Best runes in my opinion is:
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It's worth mentioning about:
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To every runes take Armour or Magic Resist. It depends on enemies you have.
If you are going to play with Press The Attack, you can choose every kind of 2nd tree.
-Choose

-Choose

3. ABILITIES
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![]() If you will use it during ending animation (auto attacks) (I talk here about kiting) you can throw fast 2 shots. It saved me many times, if you haven't tried this yet, practice that on practice tool. Also, if you will make Tumble to a wall, it will cancel animation of Q, which mean you can do 2 shots a little faster. |
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![]() If you will flash during animation of Condemn, the position, where enemy will be knocked to, will be moved, basing on your current position. Practice it on practice tool! |
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Gameplay
Early Game
As the first of all, you have to push first wave and 3 warrior minions to reach level 2. Don't push too much, your minions can't be under enemy tower. You can try to go in, if enemies have still 1st level, if they already reached level 2, let support engage, don't go in alone. Also, before level 2 you can try to poke enemy adc by auto-attacking him, but i would focus on pushing lane and reach 2nd level than enemy bot lane. When enemies will get faster 2nd level than you, you should fall back and avoid battle, if enemies won't try to poke you or go in, you can try to farm minions, but you have to be still careful.
Okay let's get into your combo at early game. It goes like this: Auto-Attack ->




If you're losing a lane
If you're winning lane
Try to poke enemies as much as you can, using your Auto-Attacks and


Mid Game
This is the time, when





Late Game



The End
Thank you for reading! Hoped you enjoyed this and learnt a lot! If you don't agree with something or you wanna discuss about any point of this guide - feel free to comment!
Follow my account - probably I will make soon, another guide for other champion!
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