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If you face a good and experient Ahri, you could be in trouble. Her E basically ruins you, avoid getting caught with it at all costs.
Akali
It depends, you know? Early game you will do lots of damage. Level 6 you most likely will lose unless she is bad. But good Akali's will probably be very dangerous. Dodge her E with your W.
Anivia
Annoying, but not an impossible lane. In this case start Q because she will poke you a lot. Dodge her Q with your W. She's very tricky because you all in on her and her passive makes you in someway vulnerable to ganks, and in some cases you won't be able to finish her off because of lack of mana/abilities. Take Presence of Mind.
Annie
Very squishy, go in on her with Brush element and when she doesn't have stun up.
Aphelios
Minor/Even. You most likely stomp early/mid game.
Ashe
Pretty much all ADC's are easy for an Assassin like Qiyana.
Azir
Super annoying. Not easy to farm and a lot of poke. Play safe.
Bard
Watchout for stun, otherwise ez.
Blitzcrank
Annoying and super dangerous. The hook makes you very vulnerable if you get hit with it. Watchout for him.
Brand
Most likely easy lane, unless he is fed.
Braum
Not a threat but very tanky.
Caitlyn
Camille
Extremely hard lane/game. Avoid her at all costs. She destroys you.
Cassiopeia
If you don't abuse of Brush element on this matchup it's a free lane for Cassio. She relies a lot on her E and AA, so Brush is perfect.
Cho'Gath
Corki
Easy, but annoying poke.
Darius
Diana
Abuse of River and Brush. She is very "tanky" and you will most likely lose lane agaisnt her. Eclipse is reliable agaisnt her.
Dr. Mundo
Draven
Brush brush brush
Ekko
His R is the most annoying thing for an Assassin like Qiyana. Only all in if he's stunned or you can stun on River/Brush.
Elise
Evelynn
Ezreal
Fiddlesticks
Fiora
Fizz
His E explains.
Galio
Ask for ganks.
Gangplank
Fed? Avoid.
Weak? Stomp.
Garen
Gnar
Gragas
Graves
Brush a lot, you can win trades very easy. E Q (Brush and wait a few sec) W Auto.
Gwen
Hecarim
Heimerdinger
Illaoi
Irelia
Ivern
Janna
Jarvan IV
Very easy to kill, if he R's you, R on his wall. It will stun him and u can all in
Jax
Jayce
Jhin
Jinx
Kai'Sa
Kalista
Karma
Karthus
Kassadin
Brush element and easy lane.
Katarina
Brush
Kayle
Kayn
Kennen
Kha'Zix
Kindred
He kites a lot and his R counters everything of your Kit.
Kled
Kog'Maw
LeBlanc
Lee Sin
Leona
Lillia
Lissandra
Depends if she's good or not.
Lucian
Lulu
Lux
Malphite
You don't win 1v1's unless he dives lmao.
Malzahar
His whole kit is a super annoying thing to face agaisnt as Qiyana.
Maokai
Master Yi
If he Q's you, R when he is about to come off of his Q.
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