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Aurelion Sol is easy to harass because of his short range. Most likely many Aurelion Sol will come up to you and will try to harass with his W ability, but go super close to him and harass him with your Q,Passive,W,Q,Passive, E,Passive and you finish him since he doesn't really have defenses except flash. When you're post 6, you can use your full combo on him. JUST DON'T LET HIS ULT RUIN YOUR COMBO!
Zoe
PROBABLY the easiest match up for Akali, if she dodges Zoe's sleepy trouble bubble, shes dead, however, some good Zoe players dodge the second part of your ult with her ultimate, then just q her when she comes back and ignite if she still has more hp.
Vel'Koz
REALLY easy, just dodge his knock up and finish him! Just don't take too much poke early game tho!
Twisted Fate
Twisted Fate usually uses his W to farm by choosing a blue card, also he tends to harass with autos. Wait for him to use the card and harass him, or W and harass him with your Q, he can't really target you with his gold card when you are invisible. However its unlikely that he hits you and you take a ton of poke!
Kayle
A decent match up, just harass when your W comes up and run when your W is almost gone or you run out of energy or she will harass you hard with her e. Also, make her use her ult before you use your second part of ult so its easier to kill her.
Irelia
Irelia mid, no problem, you counter her in general. Harass her after when she Q's on a minion and save your shroud until when she ults you, also your e flips you backwards so it's easier to dodge her e and get a better trade on her. However, she will scale late so its hard to kill her when she gets tanky.
Talon
Talon does a lot more damage than you do at levels one and two, but you can also prevent his passive by dodging the second part of his W, also use your shroud when you get hit by the second part of his w so he can't out trade you. You can save your shroud when he ults so he isn't much of a problem, just watch out for all ins when you don't have your shroud, also you out trade him when you are level 3-18.
Yasuo
He is really annoying early, if you windwalls your Q just run back until he dashes towards you and e on him twice and kill him with Q again and ignite. At post six, don't let him mess up your combo!
Veigar
His e stuns you when you e back or when you ult out, so don't use any of them since you are stunned and also it is a waste since your cooldowns are high. Just use your shroud when you are in his cage, since it gives you a move speed buff, don't let it make you get stunned, just do you combo if you tries to cage you. Also, don't let him stack up his ap or prevent him from farming.
Akali
Whoever plays the animations perfect wins since Akali is a skill shot champion. And ally, you or enemy Akali can share shrouds. THIS match up only happens in blind pick or nexus blitz.
Sona
Who even plays Sona mid anymore, but seriously, she has a ton of harass with her Q and her passive, be mindful of that since its targeted. She has utility which is kinda annoying since she has sustain, and also if you dive her be mindful of her stun.
Syndra
Easy! Unless you screw up since she punishes you hard then kills you! Before you do your combo, wait for her to use her e or she will kill you!
Zed
When he use his ult, W immediately so he doesn't stack his ult and you take a ton of damage or get one shot. Buying Zhonya is good againest him, also do your combo after he does his, he can't protect himself since he used everything up. Also e on him before he teleports with his shadow, probably will help you for an easy kill.
Karma
Just e out of her w, makes life easier. And do your combo after that.
Annie
Very predictable, wait until she uses her stun and combo her. When she FLASHES on you, your screwed or kill her before she even kills you. Watch out for Annie players who use predator or protobelt.
Morgana
Her spell shield will absorb most of your abilities, also don't get rooted or stunned since those are ridiculously long and she probably might even kill you.
Lissandra
She can be a threat but not as a good threat. She can root you or stun you but she doesn't do damage until she gets ability power. However she isn't a squishy as others so she is kinda hard to kill since she can heal her self with her ult.
Ekko
You can kill him or he can kill you if one of you plays better than the other. Save your second ult until he ults and has low hp. Pre-6, prevent him getting the third auto onto you and harass him.
Malzahar
Don't get harassed too hard and farm safely until level 6. You can buy a Quicksilver Slash to remove his supression so it doesn't do too much damage and it won't interrupt your combo, also to remove his shield without getting punished, use your e, or use w and q him then all in when you are pre 6.
Azir
Don't let him harass you too much! And kill him at post 6 since he is better at trades at early game.
Brand
Has immense harass but range is shorter than most artillery mages. DON'T get stunned. Since his combo out trades you but you can kill him a post 6.
LeBlanc
Really annoying and she can kill you when your hp is below 60%. Watch out for her w when she marks you and her chain. Good Leblanc players can 1 shot you with 3 abilities however her third ability is her w which you can dodge, however she can use chain so dodge that too. Her cool downs are long so it is easy to out trade her when she used her abilities. Also her passive makes a clone, so post 6 be sure to use the second part of your ult on the one that is correct. The clone doesn't use potions, summoner spells (except heal) so you can easily detect which is real or fake.
Katarina
Katarina out trades you at level 2 if you use your skill point on W. Her early game is deadly because of the shunpo refreshes and her slashes of her daggers. Make sure to dodge at least one dagger so she isn't deadly. Katarina can use her ultimate on you, even when your invisible, so save your ult since your 1st part of your ult is a mini stun, then finish her off.
Ryze
Don't get hit by his Q so you don't take extra damage, you can finish him post 6.
Cassiopeia
Harass Warning: she punishes you when you are low on energy and when you don't have your W up, some harass you until you run to your turret with half health. Also, most abilities are AOE so try to dodge them when you are invisible.
Orianna
Easy lane, just do your combo since her only defenses are her ultimate and her shield
Taliyah
Don't get knocked up by her w or use any dash abilities on her E, her damage is devastating. Don't get hit by her Q at least 3 times. Taliyah is a good 1 shot champion late game.
Fizz
Annoying af, don't use your of your ultimate when he becomes untargetable. Use your e to dodge his second part of his e. Or you can dodge his ult with it.
Xerath
Poke heavy, and his ultimate is hard to dodge, get a ton of magic resist for him late game. And start with a dorans shield.
Viktor
Easy lane, just don't get poked heavy or stunned, and watch out for his nukes at late game.
Kog'Maw
WHY THE HECK KOG'MAW MID IS EVEN A THING? He has way too much harass that Akali can deal with and also shreds magic resist.
Fiddlesticks
Dumb scarecrow can punish you at anytime. He can fear you to interrupt your combo and drain your health away also he can harass you from the far with his E and silences you from harassing when he uses it on you and you are close to him. He can still hit you with his ult when you are invisible.
Ahri
Decent lane, just don't get hit by her full combo. Pre 6, don't get charmed when your invisible or get hit with her Q.
Diana
WHY IS HER DAMAGE SO HIGH THAT SHE CAN ONE SHOT YOU WITH DORAN'S RING? Also she can reveal you with her e and can hit you with her W and Q.
Kassadin
Even match up, whoever does their combo perfectly or outplays better, wins.
Lux
Her combo is devastating, takes 3/4 of your hp, and most of her cool downs are short. Harass her when she goes to auto for minions or when she wasted her q. Late game, she can nuke you unless you have magic resist since she can't burst tanks. Be mindful of her roams since they are deadly. Don't get harassed too much since it can be deadly with her Q,Passive,E,Passive, and Ignite (if she brings ignite).
Anivia
Do I even need to say about her since Akali can dash over the wall and kill her and not get stunned.
Ziggs
WHY DOES HIS Q A SHIT TON OF MORE DAMAGE THAN MOST POKES AND IT BOUNCES! AND HE SLOWS YOU, ULT DOES WAY TOO MUCH AND KNOCKS YOU UP. He basically ruins your combo and does a lot of damage at the same time.
Karthus
Not really a threat unless you stay in his e for too long or get harassed too much or he won't ult you.
Gragas
Not really a threat but annoying since he ruins your combos.
Heimerdinger
You can't really kill him since he has many turrets, and he can 1 shot you after you get stunned.
Galio
Is strong against magic based champions and he has 2 abilities that can ruin you combo, especially his taunt.
Jayce
Out trades you at early levels but falls off late so its an even chance late game.
Kennen
Devastating, he can ult you when you also are invisible. Also he stuns you more than once and can really ruin your combo and his ult can't be stopped or interrupted.
Lucian
Hurts but has no cc to stop your combo and he is very squishy. But he can dodge your combos with his e.
Miss Fortune
Same as Lucian but has no mobility of self defense except a slow, but can harass you a lot.
Nidalee
I have no response to this since I don't even see Nid mid but she out trades most champions.
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