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Spells:
Flash
Ignite
Ability Order
Pyromania (PASSIVE)
Annie Passive Ability
Introduction
Marks
Greater Mark of Insight-Your basic caster marks. These are very important because when combined with your Sorcerer's Shoes, you will have 29 MPen which will cut through all but 1 of any non-tank's base MR.
Seals
Greater Seal of ReplenishmentGreater Seal of Replenishment-Gives you close to 4 MP5. This may not seem like much, but when you get down to it, this will allow you to farm harder and more efficiently and be able to poke and harass without losing too much mana.
Greater Seal of VitalityGreater Seal of Vitality-An extra boost of health that Annie could really use. The reason I don't take this over Replenishment is because we take a lot of health items in build.
Glyphs
Greater Glyph of Force-The best glyphs for this build specifically because we focus largely on early game survivability and the scaling AP this provides really helps when you're not fed or farmed.
Greater Glyph of Warding-If you find yourself getting bullied early game in lane, these will help to keep you in lane longer and reduce the damage you're taking. Both are very useful, mainly personal preference whether you want more AP or more MR.
Quintessences
Greater Quintessence of Potency-The set of these gives you as much AP as a Doran's ring and helps your early game farm and harass. Not much to say about these, they are the best quintessences for Annie in my opinion.
Greater Quintessence of Fortitude-These will give you early game health (about as much as a Doran's) and are the preferred choice if you don't want to rush/stack Doran's rings as much as the build suggests.
The only real other tree you could use would be 21-9-0 taking the same in Offence but 3 points in Resistance , 1 point in Hardiness , 4 points in Durability , and 1 final point in Veteran's Scars . This will help you have more survivability early game and Durability will help if combined with Seals of VitalitySeal of Vitality.
Another very useful setup you could use (brought to my attention by Deluth) is switching your 4 points in Mental Force for 1 point in Summoner's Wrath and 3 points in Brute Force . This will give you a slight farming advantage with the extra 3 AD and although you are down a measly 4 AP, when your Ignite is on CD, you will gain 5 AP AND AD which gives you a higher amount of AP then Mental Force would have anyways.
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