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The sustain and burst is crazy. Ekko can't really handle it unless the Vladimir is really bad.
LeBlanc
The burst is pretty crazy but not to the point that it's impossible. Just wait for her to miss her E and dodge her stuff with your own E.
Cassiopeia
She lands some poison on you and E's you to death. That, and she sustains off of it. You're melee which just means free ultimate hits if you don't watch out. Not impossible.
Swain
Same as Vladimir, but has less mobility and no pool to sink into if things get dangerous.
Kennen
You're a walking free stun. If you manage to W in time to shield some of his damage you can fight him pretty hard while his burst down.
Karthus
You have all you need to blink out of his stuff. It'll be just his AoE that hurts you but after that? You should be just fine. And you have an ultimate to deny his!
Katarina
Her Pre-6 is annoying but not impossible. Make sure her E is down and fight her. After 6 you stand a small chance but don't count on it unless you have a jungler with you.
Diana
She has a disrupt over you and a on-demand shield while yours takes time. On the upside? Your passive deals more damage than hers, and by the time she can get her 2nd passive on you during a fight all your spells should be up again and she should die!
Ahri
No charm? No life. Just don't be misled though, she still has plenty of burst. Mostly dodge able, of course.
Akali
Is she 0/0/0 around level 6? Easy. Does she have a couple of kills? Make sure to use W. Anything above those kills? Be careful. But in all cases you can still likely fight her.
Orianna
You have enough to dodge everything she has. Just be careful of the auto attack harass in the early farming levels.
Malzahar
You're gonna have a hard time after 6. Take advantage of your pre6 burst as much as possible
Mordekaiser
The hardest time is going to be when he has his spellvamp. Prior to that, try to carefully poke him down and eventually kill him.
Xerath
You have dodges. He does not. He has a stun however and should he hit it, you're going to have a bad time. But you have an E to help you with that.
Yasuo
His crits are the only annoyance in this one. Just don't be stupid and throw your only poke into his wind wall, please?
Fizz
More burst, more dodges... but could be in your favor should you play the early game right.
Heimerdinger
He's annoying, but a gank or two oughta stop him. In fights you have plenty of burst to take him down and plenty of escapes to dodge his own burst.
Kassadin
Don't get him fed, and he will only feed.
Kayle
Read Kassadin.
Syndra
Annoying but not impossible. Time your E right and you can dodge her ultimate. Otherwise just use yours to dodge most of it. Early game vs Early game.
Talon
He goes in and tries to burst. Gets you down to a quarter... and then it's your turn.
Urgot
The Q lock on is pretty insane, his slow Q and his W are annoying but eh. Not impossible. His ulti shouldn't bother you with the range on your E.
Annie
If her stun is down, fight her. If it isn't, don't. Simple.
Vel'Koz
Your E to dodge his W and his E and you should be fine. Just make sure you don't get burned down by a laser after a close fight.
Viktor
Most of his damage comes from a laser that you should be able to dodge. Just don't stand in his AoE stun.
Lux
Juke her skills and you'll be made.
Zed
Your ultimate denies his. But nonetheless his damage should be something you should be cautious of. Call for a jungler.
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