Karma can be a very viable champion especially during team fights. She is a support champ mainly as her spells aren't too powerful on the damage side unless you have a ton of AP and Magic Pen and with Karma it is always best to go with cool down reduction. With this build she will have a nice balance of AP & Magic Pen.

For Marks it is always good to go with .

Seals you have some leeway with. I usually go with , but Greater Seal of Replenishment or are both viable choices as well.

For Glyphs I go with .

Quintessences again are personal choice. I prefer , but again you could go with as well.

For masteries its a pretty straight up 9-0-21 set up. You can make whatever adjustments you want, but this is one i prefer.

There is also quite a bit off leeway with the Summoner Spells as well. The best way to choose them is to figure out before the game starts a few things.

1. What champions are on your team?
2. Who are you laning with?
3. How are you going to play Karma?

For example, say you are laning with a mana hog such as Pantheon or Malphite, or you are solo mid, your are probably going to want to take .

Or Lets say, you are laning with a squishy is a good option.

I usually take as my second spell, but is a very good second option, since playing her I have have been Exhausted quite a few times.

I think what I have above is correct for the spells, but just in case this is what you should do.

Level each ability once at the beginning. Once you hit level 4 always go for when available and then followed by

What makes Karma interesting is that her Ultimate is available at level 1 and the rest of her abilities have 6 levels to them.

There is a bunch a leeway here again with the build. I tend to go more with items that add cool down reduction and magic pen.

I always start off with . Next I go for and then .

Here you can either finish off or get first. Next I go for . Followed by .

Depending on how things are going and what you prefer, either or are both viable.

Time permitting sell of your and get your and build that into .

This is just what I use, but if you want to go more AP or more support adjust as necessary.

Karma can be key in a team fight. Using her with on an allied tank, followed by on the farthest minion, or champion away from the fight, and then using with in the mix of the battle can cause fights to be turned in your favor.

Make sure you don't get to ambitious with Karma. She may seem like she can take on the world at times, but she will get eaten a live in a team fight if you aren't careful. Of course this is true for most champs. Just keep Karma near the back of the fight. She is more viable there as she can prevent and hinder gankers coming from the rear, while the main fight is finishing.

In the laning phase using and to harass can lead to some early kills for you or your laning partner.

Karma can be viable while laning with any type of champ. She can heal, shield, and slow making her a nice laning partner.

Karma can also be used to gank. Her slow, shield, and heal make her viable for that.

Karma does have some very good qualities that are littered throughout the rest of this guide, but I will list a few more here.

Pros
-Can be very hard to kill and has excellent escape-ability
-Excellent in team fights
-Can prevent enemies from escaping
-Can heal herself and others

Cons
-When Exhausted, has hard time escaping
-Somewhat low damage output without Magic Penetration
-Not very good solo or mid. When solo can harass, but not really kill-ability

I could see Karma being a nice addition to a ranked team if your team is missing a support, or if a team wants to replace a Sivir or Nidalee or jungler.

Overall Karma is very decent champ who does take some time getting used to though. Her is key to playing her successfully and figuring out how to utilize it to its best can be difficult.

Most importantly though, have fun with Karma. She is a blast to play.

Vote how you will, but leave a comment on what needs work or what you like.