Kayle, regardless of which line it is, is sure that one is thinking about the medium or late game, since its full potential depends a lot on its objects. I will not talk about Kayle support because it is not something that should be used if you do not have some understanding of its defensive utility.

It is important to have a good understanding of farming in order to always be ahead of all the players and thus be able to buy your main items to be able to make a relevant appearance in the game.

If in early your rival went to another line and is more than 5 seconds away from where you are, just warn and keep pushing in order to have an advantage of minions and experience, so let's be clear, if you don't see a safe play or why give away a kill and possibly a double and line advantage.
f you are playing ranked and you have to go against a Kayle online my initial advice is to use champions with a lot of mobility and CC regardless of whether it is in mid or top.

The best thing to do at the top line is to use early champions like Phanteon who can spike without the need for help.

If you are the jungle, the best thing is to stop once or three times to ruin Kayle's perfect farm so that she cannot even do the Nachor's Tooth since without a finished object she cannot face a team fight without being affected by the time participation in the damage and without onting that many main Kayle do not know how to play without having the E always active.

If Kayle spends her R on an ally it is her sentence of certain death and there is no need to fear her basics if they all go on her.

Most people will use AP so one stamina item and one health item will be enough to hold it all as it will be rare for Kayle not to arm Nachor, Berzerker, and Guinzoo in that order.

If Kayle starts buying something other than Nachor's Tooth, she takes advantage of her E's active time, it's 10 seconds. that will be active and another 2 to 5 that you have to endure running from one.