So... Karma has been reworked and I played a few of games with her... One word that I can use to describe her is CRAZY! She has an AOE skill-shot, she can win almost every trade with the HP gain from her W. Her shield... OP. In a team-fight, Karma can use her ultimate and use her shield to have a 5 man shield and it also deals damage to the other team. So I decided to make an account on MOBAfire and create a Karma guild! <3.

• Greater Mark of Magic Penetration As an APC Karma, she hates people who stacks magic resists. The Mark of Magic Penetration solves this problem of people who like to stack magic resists . Regardless, Void Staff gives you tons of magic penetrations too. But having this mark on your runes can help you out alot.
• Greater Glyph of Ability Power Gives you a lot of AP in the early game. With this glyph, you can deal more damage even with out AP items to start with.
• Greater Seal of Mana Regeneration As an APC Karma, she have to spam her skills to get some free damage and gain some HP back with her W. This seal is a must have on Karma
• Greater Quintessence of Ability Power Gives you a lot of AP in the early game. This quintessence is also really common on a lot of APCs.
  

• This masterie is a pretty standard masterie on APC. This masterie gives Karma a pretty decent amount of AP, magic penetration, cooldown reduction, armor, magic resist, and health.
• I choose to put a point in Spellsword because Karma's auto-attack deals less than 60 damage at level one. Karma also runs out of mana pretty quickly, so she doesn't want to waste her mana on farming. Spellsword helps Karma to farm because it converts 5% of Karma's AP into bonus damage once she attacks.

• These are the MUST BUY items on Karma.
  Great magic penetration and also grants movement speed.
  This is Infinity Edge for AP casters. Duh!
  "IT BURNS!!! IT BURNS!!!" - Cho'Gath
  This item gives Karma some great mana regeneration and cooldown reduction.

• These are MUST BUY items on Karma too, but pick either Rod of Ages or Rylai's Crystal Scepter. pick either Void Staff, Deathfire Grasp, or Guardian Angel
  This item gives Karma more HP and MP which helps Karma to stay in fights longer.
  This item gives Karma a passive slow, some AP, and 500 HP.
  Great item for late game when magic resist is a problem.
  This item has a huge nuke that can shut down other people hard. After a target is hit by the nuke, the target's HP is decreased by 15% and takes 20% more magic damage.
  I don't think this is a great item for Karma but you can get it when you are getting focused/CC hard.

• After the rework, the passive Inner Flame has been changed.
  Passive: Gathering Fire
  Damage from Karma’s spells and basic attacks lower Mantra’s cooldown.
• After the rework, Heavenly Wave has been changed to a skill-shot called Inner Flame. Inner Flame is a skill-shot that deals magic damage and slows enemies.
  Empowered by Mantra:Soulflare – Increases damage and leaves behind a zone that slows and, after a brief delay, explodes for AoE damage.
• After the rework, Spirit Bond has been change to Focused Resolve.Focused Resolve is a enemy-targeted tether that deals damage over time. If the tether is unbroken after a short duration, the tethered target is rooted in place.
  Empowered by Mantra: Renewal – Deals bonus damage and heals Karma for the duration of the tether.
• After the rework, Soul Shield is still Soul Shield. The name has been changed to Inspire and the Empowered by Mantra effect is changed.
  Empowered by Mantra: Defiance – Enemies near the shielded ally are damaged while nearby allies are shielded and granted a short speed boost.
• After the reword, Mantra is still Mantra, except it now has a flat cool-down and it does not stack over time.

RANDOM PPP

Flash
// Teleports your champion toward your cursor's location.
// Flash is a must-have summoner spell because you can easily escape, kill secure, or to get a better position in a fight.
Ignite
// Ignites target enemy unit, dealing true damage depending on champion level over 5 seconds and reduces healing effects on the target for the duration.
// Use this to win trades and to kill secure, need to explain more?
Teleport
// After casting for 4 seconds, teleports your champion to target allied targetable item.
// Use this to get back to lane quickly without missing a single farm.
Exhaust
// Exhausts target champion, reducing their Movement Speed by 30%, Attack Speed by 50%, attack damage dealt by 30%, and ability and item damage dealt by 30% for 2.5 seconds.
// Use this to win trades and to kill secure, need to explain more?
Heal
// Restores 100-355 Health depending on champion level to your champion and to nearby allies.
// To save you and your teammates in a major fight that can win/lose the game.

In the early game, Karma

Rylai's Crystal Scepter combined with Focused Resolve is a nightmare. The passive slow from Rylai's Crystal Scepter is great combined with Focused Resolve because Focused Resolve is a damage-over-time spell so the slow apply every second from the Rylai's Crystal Scepter. This also prevents most escape from Ghost or any movement speed spells like Garen's Decisive Strike.

Rylai's Crystal Scepter <3 Focused Resolve