Hello, future Vayne users. My name is s3cret on the NA servers and my main adc is Vayne. You guys may probably already know that Vayne is an Attack Damage Carry (a.k.a. adc). How ever you may probably not know is that Vayne is also an "assasin"; an assasin is someone who assassinates someone, or basically someone who kills someone silently and quickly. This is why many people such as Doublelift from CLG and Bebe from Taipei Assassins use Vayne. Vayne can be very deadly late game, because of her W which scales better late game, than early and mid game. Alright enough with the talk lets start off with the Pros and Cons.

Regular Vayne

PROS

• Amazing Late Game
• Attack Damage and True Damage
• Has a stun, which can be used to escape
• Great passive and Ultimate for chasing
• Can go Invisible[/color]
• She is a NIGHT HUNTER!

CONS

• Really Squishy like many ADCs
• Not as great early game
• Not really the best escape as Ezreal, Corki and Graves.
• Has Red goggles instead of Black :(

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Massive DAMAGE Vayne

PROS

• Great against people who usually build Health and Armor
• Great mid - late game[/color]
• Same Pros as Regular Vayne[/color]
• Does not require a B.F Sword to do damage

CONS

• Will not take towers as fast
• Can be bad if your greatly behind
• All the other Cons as Regular Vayne

I'm doing the Basic 21/9/0 setup for Ignite, but if you are picking up cleanse it is better if you switch Butcher instead of Summoner's Wrath and Resistance instead of Summoner's Resolve . I switched these spells just for the reason that Summoner's Wrath does not effect cleanse, but Summoner's Resolve does.

Alright runes, runes are very vital to any champion and especially to an adc. Why? Well because runes can help you farm better and could possible save your life, and instead of getting a kill, you may get a double kill instead.

Regular Vayne

MARKS (aka REDS)

Greater Mark of Attack Damage

[Attack Damage]

Greater Mark of Desolation

[Armor Penetration]

SEALS (aka YELLOWS)

Greater Seal of Armor

[Armor]

GLYPH (aka BLUES)

Greater Glyph of Scaling Magic Resist

[Magic Resist per Level]

QUINTESSENCE (aka QUINTS)

Greater Quintessence of Attack Damage

[Attack Damage]

Greater Quintessence of Desolation

[Armor Penetration]

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Massive DAMAGE Vayne

MARKS (aka REDS)

Greater Mark of Attack Speed

[Attack Speed]

SEALS (aka YELLOWS)

Greater Seal of Armor

[Armor]

GLYPH (aka BLUES)

Greater Glyph of Scaling Magic Resist

[Magic Resist per Level]

QUINTESSENCE (aka QUINTS)

Greater Quintessence of Attack Damage

[Attack Damage]

Regular Vayne

Boots
Health Potion
Doran's Blade
Berserker's Greaves
Doran's Blade
Vampiric Scepter
Bloodthirster
Phantom Dancer
Infinity Edge
Guardian Angel
Phantom Dancer

Why I build Guardian Angel
I used the basic item build for any ADC, however I get Guardian Angel just because it is vital that you kept alive and the Guardian's Angel will help you continue doing damage to enemies.

Massive DAMAGE Vayne

Boots
Health Potion
Doran's Blade
Berserker's Greaves
Zeal
Phantom Dancer
Infinity Edge
Phantom Dancer
Guardian Angel
Bloodthirster

Why I go for Attack Speed instead of Attack Damage
Instead of getting two Doran's Blade and rushing damage, you get one dorans, because you need to rush zeal, because Zeal will with your w, making you do more true damage. After that you get damage.

Some items are situational!

Item's Name

Item's Stats

Situation to use it in

Madred's Bloodrazor

Can be used against a team that mostly are building health instead of armor.

Quicksilver Sash

Good against teams with stuns, slows. For example Nunu, Amumu, Galio or Skarner are champions that could get you killed really fast and that is why you buy QSS

Last Whisper ..

Last Whisper is not really a situational item, but some people skip LW and get more damage. Really the only main reason to buy it is when they the enemy team is building armor.

*NOTE*

I did not put in Black Cleaver just because, Black Cleaver is not really worth your gold, you should buy another damage or a defensive item instead.

Regular Vayne

Massive DAMAGE Vayne

Since your trying to do the most true damage, you want to max out your w instead of your q.

Flash: // Good spell to escape a gank and to ensure a kill.

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Ignite: // Good for killing people; who have heal and spell vamp. Also it is great for finish off an enemy who is near death.

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Cleanse: // Good spell to escape stuns and slows.

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Teleport: // Great for split pushing, getting back to lane and returning into a fight. However you will have to exchange a offensive or defensive spell.

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Heal: // Great to heal bait, and survivability in lane, but ignite will reduce the healing by 50 %.

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Ghost: // Good for chasing after a kill and running away from an enemy, but flash is better since you can flash over walls.

What some people don't is that it is alright if you are 10 cs behind the enemy adc. Why? Because you scale every minuite the game goes by. However in some cases you will be destroyed in early game, and all you can hope for is a lucky mistake from an enemy.

PASSIVE LANE

Here is how your gonna cs, if you have a passive lane you should try to freeze your lane right outside your tower, this way you can farm safely and the tower isn't killing the minions.

AGGRESIVE LANE

For Aggresive lane I like to just last hit, but sometimes it is okay to push, especially when your going to b, or do dragon. All you have to do is just shove your lane right into their turret, then go quickly b or help a teammate.

POKE LANE

A Poke lane should be kept around the middle as long as you have bush coverage, such as a support sitting in a bush or a ward in the bush. This way you can easily poke the enemy and farm. However if you are planning to b or help a teammate you should shove the lane to their turret, so you don't lose too much cs while you are gone.

This is very important part as Vayne.

Here is your tasks as the adc.


Friendly Initiates: // If your teammmates intitiates then you should be in a good position in the first place. .....
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Enemy Initiates: // Once the enemy initiates, your job is to get away from getting jumped on. Some teammates can also help you peel off enemies.
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After you follow one of the following steps above, you should start attacking anyone that is closest to you. *IMPORTANT* Many people think it is bad to attack the tank, as an adc you want to do as much damage as possible so it is okay if you attack an tank as long as he is the closest to you.
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Attacking Priority List (From Best to Worst)

• AD Carry
• AP Carry
• Next Squishiest Person (Usually a Support)
• Next Squishiest Person (Usually the Off-Tank)
• Tank

However in some cases you may not even attack the AD or AP carries, because the one of your teammates will have probably already killed.

Also make sure you are using your ultimate during a team fight, and tumble to help you kite or get closer to the fight.

Thats all! Thank you for looking at my guide. I hope this guide brings you success to you in the near future.

Special thanks to jhoijhoi!

Please like if you enjoyed or if this guide helped you!

Also please do comment on my mistakes and ways I should improve, but remember this is my second offical guide.