Click to open network menu
Join or Log In
Mobafire logo

Join the leading League of Legends community. Create and share Champion Guides and Builds.

Create an MFN Account






Or

It's time for the Season 13 Guide Contest! Create or update guides in the following 4 weeks for the chance to win up to $200 in prizes!

Cassiopeia Build Guides, Runes and Items

Cassiopeia The Serpent's Embrace

Find the best Cassiopeia build guides for League of Legends S13 Patch 12.23. The MOBAFire community works hard to keep their LoL builds and guides updated, and will help you craft the best Cassiopeia build for the S13 meta. Learn more about Cassiopeia's abilities, skins, or even ask your own questions to the community!

Season 4 Guides
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

CassiOPeia, The Serpents Embrace

Guide by thekatalist updated December 17, 2013
  • In-depth
5.6
3
Votes
3
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Nightcrawl's S4 Revamped Diamond 2 Cassiopeia Guide

Guide by n1gh7cr4wl updated May 8, 2014
4.7
2
Votes
4
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cass of Awesome Penetration!

Guide by Rodead updated June 14, 2014
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Slithering in the Undergrowth

Guide by MarkODea updated May 14, 2014
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassiopeia: Mid Lane Beauty - Axiomatic GG

Guide by SAWURHEAD updated December 13, 2013
Season 4 Builds
7.3
5
Votes
1
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

OP champion sportlight一Cassiopeia

Build by nghiulaam updated November 29, 2013
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Casiopeia, The Pentakilling Nuker

Build by Guest updated March 2, 2014
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Medusa's Vengeance

Build by Williamt101 updated October 25, 2014
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

olympic runner Cassiopeia

Build by 666Football666 updated September 20, 2014
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassiopeia, The Letal Snake

Build by UriahHeep updated September 1, 2014
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassiopeia

Build by Sir Gucci updated August 27, 2014
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Ultimate TOP Cassiopeia - Sir Gucci

Build by Guest updated August 27, 2014
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

PeneTratic CassioPeia

Build by JuBeST updated August 15, 2014
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassiopeia Guide

Build by Blazezaber updated August 5, 2014
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

fangs galore

Build by jaycedunker updated July 26, 2014
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

cassiopeia venom op

Build by dubix45 updated July 5, 2014
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Evil Takes a Scaly Form in Cassiopeia Du Couteau

Build by JuliaPossible updated June 30, 2014
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

The Best Bootless Cassiopeia Guide

Build by Guest updated June 26, 2014
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassiopeia - The Mythic Woman Snake

Build by JG93 updated June 4, 2014
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassiopea Near to Pentakill , Vicino alla Pentakill

Build by OniKei updated May 28, 2014
Create a Cassiopeia Build Guide Create a Cassiopeia Build Guide
Craft your own guide
Get Started

Cassiopeia Build & Runes

If you're looking for the best rune build for Cassiopeia we've got you covered. Below you can find the best items and runes to build for Cassiopeia, as determined by calculations of thousands of Plat+ League of Legends games. If you are already familiar with how to play Cassiopeia this is a great resource to quickly get a good rune selection for Patch 12.23. However, if you are a new Cassiopeia player we highly recommend reading through some of the guides above to learn why this build is strong on Cassiopeia!

Patch 12.23: 7437 matches scanned * Each section of the build is rated independently of the others

Cassiopeia's Runes

Cassiopeia's Best Runes 49%

Win Rate 1359 Games

  • 1
  • 2
  • 3
Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Last Stand
Last Stand

Resolve
LoL Path: Resolve
LoL Rune: Conditioning
Conditioning
LoL Rune: Overgrowth
Overgrowth

Second Best

Cassiopeia's 2nd Best Runes 50%

Win Rate 1234 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Last Stand
Last Stand

Sorcery
LoL Path: Sorcery
LoL Rune: Transcendence
Transcendence
LoL Rune: Manaflow Band
Manaflow Band

Third Best

Cassiopeia's 3rd Best Runes 57%

Win Rate 74 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Coup de Grace
Coup de Grace

Resolve
LoL Path: Resolve
LoL Rune: Conditioning
Conditioning
LoL Rune: Overgrowth
Overgrowth

Cassiopeia's Summoner Spells

Cassiopeia's Best Summoner Spells 49%

Win Rate 3359 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Summoner Spells 50%

Win Rate 2887 Games

Flash Teleport

Third Best

Cassiopeia's 3rd Best Summoner Spells 53%

Win Rate 1357 Games

Flash Ghost

Cassiopeia's Starters

Cassiopeia's Best Starter Items 51%

Win Rate 6915 Games

  • 1
  • 2

Trinket

Cassiopeia's Best Trinket 48%

Win Rate 5706 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Trinket 53%

Win Rate 2826 Games

Farsight Alteration

Third Best

Cassiopeia's 3rd Best Trinket 55%

Win Rate 962 Games

Oracle Lens
Don’t forget
to Buy Wards
Patch 12.23: 7439 matches scanned * Each section of the build is rated independently of the others

Cassiopeia's Runes

Cassiopeia's Best Runes 54%

Win Rate 87 Games

  • 1
  • 2
  • 3
Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Last Stand
Last Stand

Sorcery
LoL Path: Sorcery
LoL Rune: Transcendence
Transcendence
LoL Rune: Manaflow Band
Manaflow Band

Second Best

Cassiopeia's 2nd Best Runes 53%

Win Rate 85 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Last Stand
Last Stand

Resolve
LoL Path: Resolve
LoL Rune: Conditioning
Conditioning
LoL Rune: Overgrowth
Overgrowth

Third Best

Cassiopeia's 3rd Best Runes 49%

Win Rate 166 Games

Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Last Stand
Last Stand

Sorcery
LoL Path: Sorcery
LoL Rune: Transcendence
Transcendence
LoL Rune: Manaflow Band
Manaflow Band

Cassiopeia's Summoner Spells

Cassiopeia's Best Summoner Spells 62%

Win Rate 74 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Summoner Spells 54%

Win Rate 231 Games

Flash Ghost

Third Best

Cassiopeia's 3rd Best Summoner Spells 48%

Win Rate 528 Games

Flash Teleport

Cassiopeia's Starters

Cassiopeia's Best Starter Items 51%

Win Rate 974 Games

  • 1
  • 2

Trinket

Cassiopeia's Best Trinket 49%

Win Rate 769 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Trinket 55%

Win Rate 172 Games

Oracle Lens

Third Best

Cassiopeia's 3rd Best Trinket 50%

Win Rate 346 Games

Farsight Alteration
Don’t forget
to Buy Wards

Cassiopeia's Ability Order

Cassiopeia's Best Ability Order 61%

Win Rate 171 Games

  • 1
  • 2
Patch 12.22: 171634 matches scanned * Each section of the build is rated independently of the others

Cassiopeia's Runes

Cassiopeia's Best Runes 47%

Win Rate 109 Games

  • 1
Precision
LoL Path: Precision
LoL Rune: Conqueror
Conqueror
LoL Rune: Presence of Mind
Presence of Mind
LoL Rune: Legend: Tenacity
Legend: Tenacity
LoL Rune: Last Stand
Last Stand

Sorcery
LoL Path: Sorcery
LoL Rune: Transcendence
Transcendence
LoL Rune: Manaflow Band
Manaflow Band

Second Best

Cassiopeia's 2nd Best Runes 0%

Win Rate Games

LoL Path:

LoL Path:

Third Best

Cassiopeia's 3rd Best Runes 0%

Win Rate Games

LoL Path:

LoL Path:

Cassiopeia's Summoner Spells

Cassiopeia's Best Summoner Spells 59%

Win Rate 123 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Summoner Spells 53%

Win Rate 81 Games

Flash Teleport

Third Best

Cassiopeia's 3rd Best Summoner Spells 53%

Win Rate 62 Games

Flash Ignite

Cassiopeia's Starters

Cassiopeia's Best Starter Items 0%

Win Rate Games

! Small Sample Size Warning * There is either not a lot of games played on this champion or the builds vary greatly, we have provided the top build but it does not have a high confidence rating so use your own discretion.

Trinket

Cassiopeia's Best Trinket 60%

Win Rate 227 Games

  • 1
  • 2
  • 3

Second Best

Cassiopeia's 2nd Best Trinket 52%

Win Rate 67 Games

Oracle Lens

Third Best

Cassiopeia's 3rd Best Trinket 47%

Win Rate 315 Games

Stealth Ward
Don’t forget
to Buy Wards

Cassiopeia's Ability Order

Cassiopeia's Best Ability Order 0%

Win Rate Games

  • 1
! Small Sample Size Warning * There is either not a lot of games played on this champion or the builds vary greatly, we have provided the top build but it does not have a high confidence rating so use your own discretion.

Cassiopeia Counters

Learn Cassiopeia's counters and discover matchups where they have an advantage! When you're starting a game of League of Legends you should always keep in mind if you'll be at an advantage or disadvantage against your opponent, so you can know whether to bully them or play safe. You can find detailed breakdowns of each matchup on CounterStats, and you can also check out some Cassiopeia guides to see how to build and play against other champions you may find yourself up against!


This counter data is for Cassiopeia Mid in Plat+ games. The percent shown is the enemy champion's counter rating against Cassiopeia. Counter rating is our own statistic that factors in counter kills, overall kills, early lead ratio, comeback ratio, and win percent to give the whole picture of that champion's effectiveness as a counter pick.

CR is Counter Rating, which is a combination of multiple counter factors. Counters shown are for Cassiopeia Cassiopeia Mid

Cassiopeia Skins

Cassiopeia's Abilities

Questions About Cassiopeia

Ask

Latest Questions

Feeling difficult to deal damage to mages who build RoA, what should I do?

Situation: In the early-mid game, I built Morellonomicon, opponent built RoA. Problem: Feeling difficult to deal damage to opponents who build RoA. As they have higher effective health after building RoA, I feel like 'my abilities do not...

View (4) Answers

Which way is Katarina facing when she ults?

If you need the enemy to be facing you for the Cassiopoia ult to be a stun, then which way is Katarina facing while she is ulting?

View (2) Answers

Question on Cassiopeia

I want to main Cassiopeia mid to climb the ladder, but i'm far from learning anything about her besides some combos. Should I just focus on tear for the majority of early, or is it better to constantly harass my opponent? What match-ups do I...

View (2) Answers

Who should i choose?

???????????????????????? [b]Best Option[/b] ???????????????????????????????????????????? [color=#0080ff]Ahri , Cassiopeia , Diana , Ekko , Vladimir[/color]

View (3) Answers

Who is the most OP champion in the game?

I am wondering who is the most OP champion to play. I wanna see how well I can do.

View (23) Answers

What are some fun or brainless champions?

I have no idea who I should buy; any suggestions?

View (8) Answers

Was Cassiopeia recently buffed?

Title.

View (1) Answers

cassiopeia at bot lane

has anyone tried to play cassiopeia at bot lane instead of an adc? as i don't main her nor am i at a high level of play i don't know how vibiable it can become. basicly here are some thoughts: 1. as an adc cass is a sustained damaged - low...

View (4) Answers

Timing of a DoTs first "tick"

So I wanted to ask this because I couldn't find it on LoLWiki. I've been under the impression that with DoTs the first tick of damage is done on application making it so that reapplying it in rapid succession will redo the first tick of damage....

View (0) Answers

Lich bane Cass

So I've noticed that every time you use [[twin fang]] on Cass, you get an auto attack in between the .5 sec cooldowns. So i was wondering how she would fair with a [[lich bane]] as compared to other build options

View (2) Answers

Next AP Mid to learn and why?

Hey, so I can't really decide which champion to learn next after I have finished with Evelynn. I play AP Mid in a fixed 5vs5 team so I need champions who are valuable in organised competitive play. Champions I currently am able to play on a decent...

View (4) Answers

League of Legends Champions:

Teamfight Tactics Guide