Best Vayne Build Guides 2025 for LoL Patch 25.10

9.5

28
Votes
2

[S10.10] ADC Vayne, the Night Hunter - Lategame has Arrived
Guide by atonementblade updated May 13, 2020

In-depth

Rating Pending

Vayne As Perfect As Udyr
Guide by Pingu Fugindo updated April 29, 2020

9.8

79
Votes
2

Midorima's Vayne Guide (Patch 9.1) | THE SAUCE
Guide by Midorima updated March 20, 2020

In-depth

9.1

12
Votes
0

Clown Fiesta's Icy Toplane Vayne
Guide by Clown Fiesta updated March 30, 2020

8

8
Votes
1

(Portuguese Guide) High elo Main Vayne guide Patch 9.24 (g
Guide by Falllol updated December 16, 2019

8.8

17
Votes
2

Season 9 Vayne guide! Purge With Silver (9.23)
Guide by Laverenz updated November 27, 2019

In-depth

Rating Pending

Vayne [The Night Hunter] Champion Guide
Guide by mhsmhs123 updated December 7, 2019

7.8

7
Votes
1

[NEW]AssassinVayne's Special Build
Build by LSCaspen updated October 18, 2020

Rating Pending

ADC Vayne Guide Season 10
Build by Giuliano80 updated October 3, 2020

Rating Pending

VAYNE ADC/TOP
Build by Qurica updated October 4, 2020

Rating Pending

The NOOB's ARAM/SR Vayne Guide [Read Notes for SR]
Build by Crash1025 updated October 2, 2020

Rating Pending

How to play vayne.
Build by hord_on_pc updated September 25, 2020

Rating Pending

Vayne
Build by xSealed updated September 15, 2020

Rating Pending

Vayne adc
Build by oOTrrixOo updated September 13, 2020

Rating Pending

bot lane / top lane vayne
Build by adc of adc updated September 12, 2020

7.5

6
Votes
1

600k mastery points diamond Vayne guide of swag
Build by Jakobskii updated August 31, 2020

Rating Pending

Vayne the BEST build on TOP
Build by kkBono updated August 21, 2020