Best Vayne Build Guides 2025 for LoL Patch 25.11

Rating Pending

Vayne Top Lane
Build by phongvngg updated January 15, 2022

Rating Pending

[ URF ] Vayne One Hit
Build by phongvngg updated January 14, 2022

Off-Meta

Rating Pending

Vayne "BEST" runes ever!
Build by ParsaBrz updated December 8, 2021

Rating Pending

🏹👓🔴LATE GAME AND CNCER🏹👓🔴 - Vayne Build
Build by KimeraBuilds04 updated November 30, 2021

Rating Pending

Vayne
Build by CaptainSheep updated November 27, 2021

9.8

33
Votes
2

🏹 Improving your Vayne - [Patch 11.21 Ready] ✔️
Guide by 22Drift updated November 11, 2021

In-depth

Rating Pending

Ultimate Season 11 Vayne Guide [ Updated]
Guide by Vaysu updated October 16, 2021

Rating Pending

Season 11 Vayne Guide
Guide by SillyRaccoom14 updated September 13, 2021

8.8

17
Votes
2

Calculus Optimized Vayne
Guide by fanchessfan updated August 7, 2021

In-depth

Rating Pending

Unique One Shot Invisible Vayne
Guide by Jeretar updated August 8, 2021

7.1

19
Votes
9

[10.20] Top Lane Vayne: Abusing CDR
Guide by Seth346 updated July 29, 2021

In-depth

Rating Pending

Vayne ADC Guide Season 11 v11.15
Guide by banewastaken updated July 27, 2021

8.8

31
Votes
5

[11.13] Kewllkiddo's Diamond Season 11 Vayne Guide
Guide by Harambe Homie updated July 2, 2021

In-depth

8.9

144
Votes
10

[11.12] THE ULTIMATE S11 GRANDMASTER Vayne Guide!
Guide by DoublefeedOP updated June 22, 2021

In-depth

Rating Pending

{D2} Vayne Jungle Main
Guide by Mr.Dragon updated May 30, 2021

7.7

9
Votes
2

S11.7 Vayne the Lethal Vampire Hunter
Guide by dewdong updated April 2, 2021

6.8

16
Votes
9

S11.7 Vayne the Tank Engine
Guide by dewdong updated April 2, 2021

Off-Meta

8

8
Votes
1

A COMPLETE guide to Vayne, our favourite ADC!
Guide by ctm20141 updated March 18, 2021

In-depth