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Thrashing Thresh Support.
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8 of the .25g/10 seals gives 2 gold/10.
3 of the 1g/10 quintessences gives 3 gold/10.
= total of 5g/10.
1 of the 1.41 armor seal.
9 if the .91 armor marks.
9 of the .7 armor glyphs.
= total of 15.9 armor.
In the defense tree the main talents (in my opinion) are the reduced tower damage, reduced slow amount, reduced cc time, and increased max health.
In the support tree the main talents are the gold per ten, mana regeneration and summoner spell cdr.
This way you can remain in the fight longer and not be as harshly hindered by enemies and spam your summoner spells almost every fight while still being able to get your items quicker and not running out of mana.
From there you get choices.
I prefer soul shroud and sunfire cape for the extra health, health regen and resistances as i am usually main tank. Guardian Angel is also a good item in this space, which i would replace sunfire cape for since you can farm armor with your passive.
If you are not main tank, and want to focus in damage you can go for rylai's crystal scepter or abyssal scepter, or possibly (but i dont care for it) rabbadon's deathcap
And lastly, if you are not main tank and want to focus support you can go for zeke's herald or will of the ancients to increase your team's damage OR locket of the iron solari and mikael's crucible for extra team durability in those team fights.
Flash can help you set up plays or escape. With the 10% summoner spell crd and the 15 seconds lower cd from the support tree you can use it a lot.
Exhaust helps protect your allies or helps secure a kill, a great tool for any support.
I like to see heal, clairvoyance or teleport on thresh.
Heal helps keep your team alive as a support should do.
Clairvoyance gives you that extra eye in the sky, preventing ganks and barron attempts all game long.
Teleport allows for quick movement around the battlefield, never being too far from that team fight breaking out when you are needed.