Best Vayne Build Guides 2025 for LoL Patch 25.09

9.8

79
Votes
2

Midorima's Vayne Guide (Patch 9.1) | THE SAUCE
Guide by Midorima updated March 20, 2020

In-depth

9.1

12
Votes
0

Clown Fiesta's Icy Toplane Vayne
Guide by Clown Fiesta updated March 30, 2020

8

8
Votes
1

(Portuguese Guide) High elo Main Vayne guide Patch 9.24 (g
Guide by Falllol updated December 16, 2019

8.8

17
Votes
2

Season 9 Vayne guide! Purge With Silver (9.23)
Guide by Laverenz updated November 27, 2019

In-depth

Rating Pending

Vayne [The Night Hunter] Champion Guide
Guide by mhsmhs123 updated December 7, 2019

7.8

7
Votes
1

[NEW]AssassinVayne's Special Build
Build by LSCaspen updated October 18, 2020

Rating Pending

ADC Vayne Guide Season 10
Build by Giuliano80 updated October 3, 2020

Rating Pending

VAYNE ADC/TOP
Build by Qurica updated October 4, 2020

Rating Pending

The NOOB's ARAM/SR Vayne Guide [Read Notes for SR]
Build by Crash1025 updated October 2, 2020

Rating Pending

How to play vayne.
Build by hord_on_pc updated September 25, 2020

Rating Pending

Vayne
Build by xSealed updated September 15, 2020

Rating Pending

Vayne adc
Build by oOTrrixOo updated September 13, 2020

Rating Pending

bot lane / top lane vayne
Build by adc of adc updated September 12, 2020

7.5

6
Votes
1

600k mastery points diamond Vayne guide of swag
Build by Jakobskii updated August 31, 2020

Rating Pending

Vayne the BEST build on TOP
Build by kkBono updated August 21, 2020

Rating Pending

GOSU Vayne Build
Build by Nothing here updated August 19, 2020

Rating Pending

Best Vayne Top Builds/Runes Challenger
Build by Homerjsinpso updated July 30, 2020