Click to open network menu
Join or Log In
Mobafire logo

Join the leading League of Legends community. Create and share Champion Guides and Builds.

Create an MFN Account


MOBAFire's final Season 13 Mini Guide Contest is here! Create or update guides for the 30 featured champions and compete for up to $200 in prizes! 🏆
Cassiopeia Build Guide by Flipps

Middle Anithero Cassiopeia Guide

Middle Anithero Cassiopeia Guide

Updated on April 9, 2022
New Guide
Vote Vote
League of Legends Build Guide Author Flipps Build Guide By Flipps 6,820 Views 0 Comments
6,820 Views 0 Comments League of Legends Build Guide Author Flipps Cassiopeia Build Guide By Flipps Updated on April 9, 2022
Did this guide help you? If so please give them a vote or leave a comment. You can even win prizes by doing so!

You must be logged in to comment. Please login or register.

I liked this Guide
I didn't like this Guide
Commenting is required to vote!
Would you like to add a comment to your vote?

Your votes and comments encourage our guide authors to continue
creating helpful guides for the League of Legends community.

Runes: For non-tear builds

1 2 3 4 5 6 7 8 9
Phase Rush
Manaflow Band
Gathering Storm

Second Wind

+9 Adaptive (5.4 AD or 9 AP)
+6 Armor
+6 Armor


1 2 3 4 5 6 7
LoL Summoner Spell: Exhaust


LoL Summoner Spell: Flash



Threats & Synergies

Threats Synergies
Extreme Major Even Minor Tiny
Show All
None Low Ok Strong Ideal
Extreme Threats
Ideal Synergies
Ideal Strong Ok Low None

Champion Build Guide

Anithero Cassiopeia Guide

By Flipps
you can charge R and then flash to catch people off guard. i.e. from walls, or while chasing someone (to get slow or stun if lucky). Works best if they think you're running away. You can also R backwards and flash behind them.

you need to throw out autos in between Es while chasing someone. This has the biggest effect early game.

If your laner just left lane to go roam, warn the lane and push your wave as often times you wont have the mobility to follow up, and having their wave pushed in can make them come back. Additionally, you can push and look for a TP.

Learn to use miasma effectively, it is by far her most versitile ability.

Try not to rely on the stun from her R, good players will turn around.
About Me
I am a cassiopeia OTP. I was drawn to cassiopeia from her challenging mechanics. As most of us cassiopeia mains will agree, the difference between being a cassiopeia and a random snake is landing abilities. In order to get multi kills and such you need to chain your Qs and space like a madmad. When I was finally able to play her well, it gave me lots of adrenaline to pull of flashy plays, and kite well, and in turn helped me become better at this game. I started only playing cassiopeia, learning matchups, getting better and better and better, until eventually I realized I was a OTP and I gave in.

A couple seasons ago with the item changes, Cassiopeia was hit hard. She essentially needed to spend an extra 3000 gold to get into the game, and along with meta changes to favour earlygame comps, constant nerfs to items, runes, and the sustain system, and burst damage going up, she has become very difficult to play, often being a situational pick. Being an OTP, I was forced to adapt in any way possible. Often times you will see cassiopeia mains suck it up and build liandries into seraphs, I couldn't stand that build so I made a couple of my own. I will admit that my builds might not be superior to the standard, but It does retain my playstyle from when I learned her. Overall, I'd say that if you tried cass and didn't like her, try one of my builds. Additionally, if you already play her, it might teach you a thing or two to utilize muramana.

Sincerely, Flippy.
Download the Porofessor App for Windows
League of Legends Build Guide Author Flipps
Flipps Cassiopeia Guide
Vote Vote
Anithero Cassiopeia Guide

League of Legends Champions:

Teamfight Tactics Guide