Hi, guys, I am ShockBlade aka strikereureka123 at EUNE server. I am a solo Q Kha'Zix main, and in S4 i am ranked Silver V. I know it's not perfect, but i don't really play a whole lot of ranked, so no judges pls. As first before the guide starts, English is not my native language so i will be glad if u find some mistakes in my text and correct them in the comments.

Here's my acc on LoLKing:
http://www.lolking.net/summoner/eune/42005609#profile

Kha is a meele assasin/fighter. He has a great late game phase, specially if u get fed. An interesting thing about Kha is that he is a blood enemy with Rengar Rengar. If the enemy team has a Rengo then both, Kha and Rengar get a quest at the beggining of game to kill eachoter. If Rengar completes the quest he gets bonus stacks on his Bonetooth Necklace and Kha gets a fourth evolve.

Pros:
-He has good CC with W and passive
-He has high mobility with ult and E
-High damage burst to isolated targets
-Great gank potential

Cons:
-Has a rough time early game specially vs ranged champs
-Pretty squishy when not doing tanky builds
-Can't enter teamfights safely when being focused

Greater Quintessence of Attack Damage
Greater Quintessence of Movement Speed
greater quintessence of armor penetration
For the most important runes-Quints i take AD Runes, which are kind of a meta for AD champs. A nice replacement would be maybe MS Quints since they are good for Jungle Rune pages.

Greater Mark of Attack Damage
greater mark of armor penetration
For runes i use AD marks, a pretty standard choice for AD rune pages. Also Armor Pen marks are a reliable choice, since at top lane or jungle there are a lot of tanks stacking armor.

Greater Seal of Armor
Greater Seal of Health
For Seals i take Armor seals, also a pretty standard choice for all rune pages not just AD. Also a reliable choice to replace them with are HP seals, which are IMO not as useful.

Greater Glyph of Magic Resist
Greater Glyph of Cooldown Reduction
For Glyphs i take MR glyphs. A nice replacement would be Scaling MR Glyphs or CDR Glyphs for a nice amount of Cooldown. It's useful for your E since it has a 19 sec CDR at level 1.

The masteries i use on Kha are my AD Assasin page masteries. I find them very good on him.

For masteries in Offensive tree i take a mix of damage from spells and basic attacks Brute Force Martial Mastery Warlord Havoc , cooldown reduction Sorcery, a bit of lifesteal Feast Dangerous Game . U could also use some AS Fury but i don't find it as useful on this champion.

In Def. tree i use a standard mix reliable on all mastery pages with 9 points in defense, a mix of health Veteran's Scars Juggernaut , health regen Recovery , armor Block Unyielding (reduced dmg from basic attacks taken).

I don't pref taking anything in the utility tree, because it isn't very useful. I mean u can use it if u want CDR or Movespeed for example, but i don't prefer it. But if u really want to use your points in the utility tree then use that page only for jungling. Reliable choices are: Fleet of Foot Meditation Summoner's Insight Runic Affinity .

Reliable Starting items:
Doran's Blade or Doran's Shield for defensive start.
Long Sword for offensive start.
Faerie Charm if rushing Tear of the Goddess- Manamune- Muramana
Hunter's Machete if jungling.

Offensive items:
Ravenous Hydra gives a great passive and active for more burst damage.
Upgrade your The Brutalizer to Black Cleaver or Youmuu's Ghostblade as soon as possible for extra DMG, Armor Pen, CDR, and Crit Chance if taking Youmuu's Ghostblade.
Last Whisper-a great choice if enemy team is stacking armor.
Bloodthirster a great damage and lifesteal item, got better at the last few patches.
Trinity Force-an item that gives tons of dmg, has a nice passive, and it's good on Kha forever.
Spirit of the Elder Lizard a great jungling item for Kha.

Defensive items:
Randuin's Omen gives nice nice health, armor, slow with passive and active.
Maw of Malmortius gives nice AD and MR. Upgrade it from Hexdrinker as your last item. The gold for the upgrade is better to spend on something else in early game. It's not worth the price anyways.
Guardian Angel-great armor and mr + a bonus life, what else do you need?

Max W (Void Spikes) first on Kha, because his Q was nerfed, and W got better. Evolve W first too, it has an amazing dmg output and it can hit multiple targets. Evolved W+ Ravenous Hydra-great wave clear.

Max Q (Taste Their Fear) second. In my opinion, it's not as strong as W, but it recently got buffed so it has a decent amount of dmg, too. And it's worth maxing 'cuz the amazing damage to isolated targets.
Evolve Q or ult third.

Max E (Leap) last, because it's your least damage deal ability. Evolve E second, IMO it's the best choice for the second evolve because it gives bonus range for the jump, and resets E every time he gets a kill or assist.

Max R-your ultimate (Void Assault) every time u have a chance (at levels 6,11 and 16). It gives u stealth and bonus movespeed for 1 sec for 2 times (2 seconds, can be cast 3 times if evolved) and it gives u passive.

For regular spells i take Ignite and Flash. Other options are Teleport for top lane, Ghost if u are at lower level than 12 or if jungling (it's not a viable laning choice). At one of the last updates, double Exhaust has became a very popular choice (one Exhaust for support and one for some other team member-not viable for ADCs), so Exhaust is a viable spell too. U must take Smite if jungling, because it secures buffs, dragons and barons.

Thank you for reading this guide, i hope you all enjoyed it and that it will help you rule all Kha'Zix techniques and mechanics or add him to your champion pool. Good luck and have fun at the Fields of Justice!!!